BSP-16 is a stimulator of interferon genes (STING) agonist.1 It binds to STING (Kd = 23 µM) and induces the production of IFN-β, IL-6, and chemokine (C-X-C motif) ligand 10 (CXCL10) in THP-1 cells when used at concentrations of 10, 25, and 50 µM. BSP-16 (50 µM) induces phosphorylation of IFN regulatory factor 3 (IRF3) and TANK-binding kinase 1 (TBK1) in THP-1 cells. In vivo, BSP-16 (15 and 30 mg/kg) reduces tumor volume in an MC-38 murine carcinoma model and induces tumor regression in a CT26 murine colorectal carcinoma model. It prevents tumor cell re-challenge-induced tumor formation in a CT26 murine carcinoma model. BSP-16 (20 mg/kg) also reduces tumor volume and increases the number of activated CD8+ T cells and natural killer (NK) cells in a 4T1 murine mammary carcinoma model.
BSP-16
Catalog No.: GC90705Purity:>98.00%
A STING agonist
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2727249-47-8
500 μgIn Stock
$213.00
1
1 mgIn Stock
$405.00
1
5 mgIn Stock
$1,385.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 500 μg | $213.00 | In Stock | 1 | |
| 1 mg | $405.00 | In Stock | 1 | |
| 5 mg | $1,385.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>98.00%Appearance:A solid
Chemical Properties
CAS No.
2727249-47-8
Molecular Formula
C16H18O5Se
Molecular Weight
369.3
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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