GLPBio

BVDU 5′-Triphosphate ammonium

Catalog No.: GC85007Purity:>98.00%Synonyms: (E)-5-(2-Bromovinyl)-dUTP ammonium; BVdUTP ammonium
COASDSData Sheet
BVDU 5′-Triphosphate ammonium is an antivirus agent with 5′-Triphosphate label, targeting viral DNA polymerase.

Products are for research use only. Not for human use. We do not sell to patients.

BVDU 5′-Triphosphate ammonium
1mgIn Stock
$123.00
1
5mgIn Stock
$270.00
1
10mgIn Stock
$432.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

BVDU 5′-Triphosphate ammonium is an antivirus agent with 5′-Triphosphate label, targeting viral DNA polymerase. BVDU 5′-Triphosphate ammonium shows excellent selectivity against varicella-zoster virus ( VZV ) and herpes simplex virus type 1 ( HSV-1 ), due to a specific phosphorylation by the virus-encoded thymidine kinase.

References:
[1]. De Clercq E. Discovery and development of BVDU (brivudin) as a therapeutic for the treatment of herpes zoster. Biochem Pharmacol. 2004 Dec 15;68(12):2301-15.

Product Documents

Purity:>98.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

Synonyms
(E)-5-(2-Bromovinyl)-dUTP ammonium; BVdUTP ammonium
Molecular Formula
C11H19BrN3O14P3
Molecular Weight
590.11
Solubility
H2O: 250 mg/mL (423.65 mM; Need ultrasonic)
Storage
Store at -20°C, stored under nitrogen, away from moisture
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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