C-telopeptide acetate is a cross-linked peptide of type I collagen that is released during bone resorption and correlates with bone mineral density (BMD). C-telopeptide acetate can be used in studies related to postmenopausal osteoporosis [1] [2] [3].
In Vitro, C-telopeptide (1-100 ng/mL; overnight, 2 h, 30 min) acetate ELISA exhibits high sensitivity (0.3 ng/mL) for detecting synthetic rat C-telopeptide in vitro[2].
References:
[1]. Shieh A, et al. Changes in Collagen Type I C-Telopeptide and Procollagen Type I N-Terminal Propeptide During the Menopause Transition. J Clin Endocrinol Metab. 2024 May 17;109(6):1580-1589.
[2]. Srivastava AK, et al. Development and application of a serum C-telopeptide and osteocalcin assay to measure bone turnover in an ovariectomized rat model. Calcif Tissue Int. 2000 Jun;66(6):435-42.
[3]. Yamaga A, et al. Changes in urinary excretions of C-telopeptide and cross-linked N-telopeptide of type I collagen during pregnancy and puerperium. Endocrine journal. 1997 Oct;44(5):733-8.
In Vitro, C-telopeptide (1-100 ng/mL; overnight, 2 h, 30 min) acetate ELISA exhibits high sensitivity (0.3 ng/mL) for detecting synthetic rat C-telopeptide in vitro[2].
References:
[1]. Shieh A, et al. Changes in Collagen Type I C-Telopeptide and Procollagen Type I N-Terminal Propeptide During the Menopause Transition. J Clin Endocrinol Metab. 2024 May 17;109(6):1580-1589.
[2]. Srivastava AK, et al. Development and application of a serum C-telopeptide and osteocalcin assay to measure bone turnover in an ovariectomized rat model. Calcif Tissue Int. 2000 Jun;66(6):435-42.
[3]. Yamaga A, et al. Changes in urinary excretions of C-telopeptide and cross-linked N-telopeptide of type I collagen during pregnancy and puerperium. Endocrine journal. 1997 Oct;44(5):733-8.