GLPBio

C9-200

Catalog No.: GC92077Purity:>95.00%
COASDSData Sheet
C9-200 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNPs).

Products are for research use only. Not for human use. We do not sell to patients.

C9-200
1 mgIn Stock
$41.00
1
5 mgIn Stock
$143.00
1
10 mgIn Stock
$244.00
1
25 mgIn Stock
$456.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

C9-200 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNPs).1 LNPs containing C9-200 and encapsulating mRNA encoding erythropoietin (EPO) increase serum EPO levels in mice. LNPs containing C9-200 and encapsulating mRNA encoding the Cas9 nuclease and small-guide RNA (sgRNA) targeting transthyretin (TTR) induce 3-fold higher hepatic insertion and deletion (indel) formation than LNPs containing C12-200 and encapsulating mRNA encoding Cas9 in mice.

References:
[1]. Mrksich, K., Padilla, M.S., Joseph, R.A., et al.Influence of ionizable lipid tail length on lipid nanoparticle delivery of mRNA of varying lengthJ. Biomed. Mater. Res. A112(9)1494-1505(2024).

Product Documents

Purity:>95.00%Appearance:A solution in ethanol
COASDSData Sheet

Chemical Properties

Chemical Name
1,1'-((2-(4-(2-((2-(bis(2-hydroxynonyl)amino)ethyl)(2-hydroxynonyl)amino)ethyl)piperazin-1-yl)ethyl)azanediyl)bis(nonan-2-ol)
SMILES
OC(CCCCCCC)CN(CCN(CC(CCCCCCC)O)CC(CCCCCCC)O)CCN1CCN(CCN(CC(CCCCCCC)O)CC(CCCCCCC)O)CC1
Molecular Formula
C55H115N5O5
Molecular Weight
926.5
Solubility
Ethanol: Sparingly soluble: 1-10 mg/ml
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

Reviews

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