GLPBio

CAD031

Catalog No.: GC70562Purity:>99.00%
CAD031 is a derivative of the Alzheimer's disease (AD) targeting agent J147 with neuroprotective and memory-enhancing properties.

Products are for research use only. Not for human use. We do not sell to patients.

CAD031
Cas No.: 2071209-49-7
10mM (in 1mL DMSO)In Stock
$119.00
1
5 mgIn Stock
$108.00
1
10 mgIn Stock
$162.00
1
25 mgIn Stock
$315.00
1
50 mgIn Stock
$504.00
1
100 mgIn Stock
$810.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

CAD031 is a derivative of the Alzheimer's disease (AD) targeting agent J147 with neuroprotective and memory-enhancing properties. CAD031 enhances memory in mice, improves dendritic structure, and stimulates cell division in the germinal zone of the brain in aged mice. CAD031 is more active than J147 in human neural stem cell assays.

References:
[1]. Prior M, et al. Selecting for neurogenic potential as an alternative for Alzheimer's disease drug discovery. Alzheimers Dement. 2016 Jun;12(6):678-86.

Product Documents

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Purity:>99.00%Appearance:A solid

Chemical Properties

CAS No.
2071209-49-7
Molecular Formula
C18H14F6N2O2
Molecular Weight
404.31
Solubility
DMSO : 100 mg/mL (247.33 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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