GLPBio

Caffeoyltryptophan

Catalog No.: GC71869Purity:>96.00%
COASDSData Sheet
Caffeoyltryptophan is a competitive PTP1B inhibitor, with an IC50 of 16.99 μM.

Products are for research use only. Not for human use. We do not sell to patients.

Caffeoyltryptophan
Cas No.: 109163-69-1
1 mgIn Stock
$117.00
1
5 mgIn Stock
$261.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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    31, 1291–1307 (2021)

Description

Caffeoyltryptophan is a competitive PTP1B inhibitor, with an IC50 of 16.99 μM. Caffeoyltryptophan can also inhibit α-glucosidase, linoleic acid peroxidation and haemolysis. Caffeoyltryptophan can be used for the research of type 2 diabetes.

References:
[1]. Ha MT, et, al. PTP1B and α-glucosidase inhibitory activities of the chemical constituents from Hedera rhombea fruits: Kinetic analysis and molecular docking simulation. Phytochemistry. 2022 May:197:113100.
[2]. Ohnishi M, et, al. Inhibition in vitro linoleic acid peroxidation and haemolysis by caffeoyltryptophan. Phytochemistry. 1998 Apr;47(7):1215-8.

Product Documents

Purity:>96.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
109163-69-1
Molecular Formula
C20H18N2O5
Molecular Weight
366.37
Solubility
DMSO : 100 mg/mL (272.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Storage
4°C, protect from light
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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