GLPBio

Glucosidase

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Glucosidases are glycoside hydrolase enzymes.

α-glucosidase is a glucosidase located in the brush border of the small intestine that acts upon α(1→4) bonds. α-Glucosidase inhibitor is a new type of antidiabetics. By reducing the postprandial blood sugar concentration, it can effectively control the blood sugar levels, thereby reducing the occurrence of diabetic complications.

β-glucosidase catalyzes the hydrolysis of the glycosidic bonds to terminal non-reducing residues in β-D-glucosides and oligosaccharides, with release of glucose. β-Glucosidase has attracted substantial attention in the scientific community because of its pivotal role in cellulose degradation, glycoside transformation and many other industrial processes. β-glucosidases catalyze the final step of cellulose hydrolysis and are essential in cellulose degradation.

Products Related to Glucosidase(47)

  • GC18007 structure
    GC18007Voglibose
    CAS: 83480-29-9
    Purity: >98.00%

    α-glucosidases inhibitor

  • GC18058 structure
    GC18058Conduritol B epoxide
    CAS: 6090-95-5
    Purity: >97.00%

    β-glucosidase inhibitor

  • GC30277 structure
    GC302774',5-Dihydroxyflavone
    CAS: 6665-67-4
    Purity: >98%

    4',5-Dihydroxyflavone is a soybean LOX-1 and yeast α-Glucosidase inhibitor, with an Ki of 102.6 μM for soybean LOX-1 and an IC50 of 66 μM for yeast α-glucosidase.

  • GC30637 structure
    GC30637N-Methylmoranoline (MOR 14)
    CAS: 69567-10-8
    Purity: >98%

    N-Methylmoranoline (MOR 14) (MOR 14) is an α-glucosidase inhibitor.

  • GC31580 structure
    GC31580Cefetrizole
    CAS: 65307-12-2
    Purity: >98%

    Ceftezole is an α-Glucosidase inhibitor with an IC50 and a Ki of 2.1 μM and 0.578 μM, respectively.

  • GC32074 structure
    GC32074Celgosivir hydrochloride (MBI 3253 (hydrochloride))
    CAS: 141117-12-6
    Purity: >98.00%

    Celgosivir hydrochloride (MBI 3253 (hydrochloride)) (MBI 3253 hydrochloride; MDL 28574 hydrochloride; MX3253 hydrochloride) is an α-glucosidase I inhibitor; inhibits bovine viral diarrhoea virus (BVDV) with an IC50 of 1.27 μM in in vitro assay.

  • GC32191 structure
    GC32191Celgosivir (MBI 3253)
    CAS: 121104-96-9
    Purity: >98%

    Celgosivir (MBI 3253) (MBI 3253; MDL 28574; MX3253) is an α-glucosidase I inhibitor; inhibits bovine viral diarrhoea virus (BVDV) with an IC50 of 1.27 μM in in vitro assay.

  • GC34835 structure
    GC34835Terphenyllin
    CAS: 52452-60-5
    Purity: >98%

    A fungal metabolite with antibacterial properties

  • GC35553 structure
    GC35553Brevifolincarboxylic acid
    CAS: 18490-95-4
    Purity: >99.50%

    Brevifolincarboxylic acid is extracted from Polygonum capitatum, has inhibitory effect on the aryl hydrocarbon receptor (AhR).

  • GC36165 structure
    GC36165Glycyrrhisoflavone
    CAS: 116709-70-7
    Purity: >98.00%

    Glycyrrhisoflavone, an active prenylflavonoid, inhibits α-glucosidase.

  • GC36347 structure
    GC36347Isotanshinone I
    CAS: 20958-17-2
    Purity: >98%

    Isotanshinone I has inhibitory activity against α-glucosidase and formation of AGE, with IC50s of 1.13 μM and 0.432 μM for α-glucosidase and AGE, respectively.

  • GC36375 structure
    GC36375Kaempferol 3-O-gentiobioside
    CAS: 22149-35-5
    Purity: >99.50%

    Kaempferol 3-O-gentiobioside is a flavonoid isolated from C.

  • GC38046 structure
    GC38046Gitogenin
    CAS: 511-96-6
    Purity: >99.50%

    Gitogenin is a natural steroid isolated from the whole plant of Tribulus longipetalus.

  • GC38279 structure
    GC38279Cedryl acetate
    CAS: 77-54-3
    Purity: >95.00%

    Cedryl acetate is a tricyclic sesquiterpene isolated from the plant Psidium caudatum.

  • GC38995 structure
    GC38995Panasenoside
    CAS: 31512-06-8
    Purity: >98%

    Panasenoside is a flavonoid isolated from Lilium pumilum D.

  • GC39233 structure
    GC39233Butyl isobutyl phthalate
    CAS: 17851-53-5
    Purity: >97.00%

    Butyl isobutyl phthalate is isolated from the rhizoid of Laminaria japonica.

  • GC39795 structure
    GC39795(+)-Afzelechin
    CAS: 2545-00-8
    Purity: >98.00%

    (+)-Afzelechin, isolated from rhizomes of Bergenia ligulata, is an alpha-glucosidase activity inhibitor with an ID50 (50% inhibition dose) value of 0.13 mM.

  • GC41992 structure
    GC419921-Deoxynojirimycin (hydrochloride)
    CAS: 73285-50-4
    Purity: >98.00%

    1-Deoxynojirimycin (1-dNM) (hydrochloride), produced by Bacillus species, is a glucose analog that potently inhibits α-glucosidase I and II.

  • GC60706 structure
    GC60706Chrysophanol triglucoside
    CAS: 120181-07-9
    Purity: >98%

    Chrysophanol triglucoside is an anthraquinone isolated from Cassia obtusifolia, inhibits protein tyrosine phosphatases 1B (PTP1B) and α-glucosidase with IC50s of 80.17 and 197.06 ?M, respectively.

  • GC60802 structure
    GC60802Eleutherol
    CAS: 480-00-2
    Purity: >98%

    Eleutherol is a naphthalene isolated from E.

  • GC61242 structure
    GC61242Resveratroloside
    CAS: 38963-95-0
    Purity: >98%

    Resveratroloside is a competitive inhibitior of α-glucosidase with an IC50 of 22.9 μM.

  • GC61635 structure
    GC61635Kaempferol-7-O-rhamnoside
    CAS: 20196-89-8
    Purity: >98.00%

    Kaempferol-7-O-rhamnoside, isolated from Chimonanthus nitens Oliv.

  • GC61697 structure
    GC61697Naringinase
    CAS: 9068-31-9
    Purity: >98.00%

    Naringinase is a complex enzyme with dual activities of α-L-rhamnosidase and β-D-glucosidase.

  • GC62551 structure
    GC62551β-Hydroxypropiovanillone
    CAS: 2196-18-1
    Purity: >98.00%

    β-Hydroxypropiovanillone, a natural compound, shows significant concentration-dependent inhibitory effects on α-glucosidase with an IC50 of 257.8 μg/mL.