CAY10486 (Synonyms: 4Hydroxycinnamic acid (Lphenylalanine methyl ester) amide) |
| Catalog No.GC40869 |
Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis.
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Cas No.: 615264-52-3
Sample solution is provided at 25 µL, 10mM.
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Acyl-Coenzyme A: cholesterol acyltransferase-1 and -2 (ACAT-1 and ACAT-2) catalyze the formation of cholesterol esters from cholesterol and long chain fatty acyl-coenzyme A, and may play a role in the development of atherosclerosis. CAY10486 inhibits human ACAT-1 and ACAT-2 equally with an IC50 value of approximately 60 µM. It also inhibits copper-mediated oxidation of low density lipoproteins by about 28% at a concentration of 3 µM.
Average Rating: 5 (Based on Reviews and 2 reference(s) in Google Scholar.)
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