GLPBio

CHD1L-IN-2

Catalog No.: GC79030Purity:>98%
COASDSData Sheet
CHD1L-IN-2 is a CHD1L inhibitor and exhibits cytotoxicity against tumor cells [1] [2].

Products are for research use only. Not for human use. We do not sell to patients.

CHD1L-IN-2
Cas No.: 1251542-88-7
1mgIn Stock
$864.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
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    Nature
    641, 529–536 (2025)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

CHD1L-IN-2 is a CHD1L inhibitor and exhibits cytotoxicity against tumor cells [1] [2].

In Vitro, CHD1L-IN-2 (Compound 6.3) (72 h) has IC50 values of 3.6 and 3.7 μM for SW620 and HCT116 cells[1].

References:
[1]. Daniel V. LABARBERA, et al. Small molecule inhibitors of oncogenic chd1l with preclinical activity against colorectral cancer. WO2023055763A2. 2023-04-06.
[2]. Prigaro BJ, et al. Design, Synthesis, and Biological Evaluation of the First Inhibitors of Oncogenic CHD1L. J Med Chem. 2022 Mar 10;65(5):3943-3961.

Chemical Properties

CAS No.
1251542-88-7
Molecular Formula
C24H24N6O
Molecular Weight
412.5
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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