COMT

COMT (catechol-O-methyltransferase) is one of several enzymes that degrade catecholamines such as dopamine, epinephrine, and norepinephrine.

Products Related to COMT(11)

GC18091 Entacapone sodium salt
CAS: 1047659-02-8
Purity: >98%
COMT inhibitor
GC12535 Flopropione
CAS: 2295-58-1
Purity: >98.50%
5-HT receptor antagonist
GC14223 Nitecapone
CAS: 116313-94-1
Purity: >99.00%
S-COMT inhibitor
GC14843 Serotonin HCl
CAS: 153-98-0
Purity: >98.00%
Serotonin HCl a neurotransmitter, is a key messenger that mediates several central and peripheral functions in the human body.
GC17334 Entacapone
CAS: 130929-57-6
Purity: >98.00%
Entacapone is a potent, reversible, peripherally acting and orally active inhibitor of catechol-O-methyltransferase (COMT), which effectively inhibits rat liver total COMT with IC 50 and K i values of 20.1nM and 10.7nM, respectively.
GC17921 Tolcapone
CAS: 134308-13-7
Purity: >98%
A reversible COMT inhibitor
GC36811 Opicapone
CAS: 923287-50-7
Purity: >99.50%
A COMT inhibitor
GC62809 5-Hydroxyferulic acid
CAS: 1782-55-4
Purity: >98%
5-Hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway.
GC65175 Nebicapone
CAS: 274925-86-9
Purity: >99.00%
Nebicapone (BIA 3-202), a reversible catechol-O-methyltransferase (COMT) inhibitor, is mainly metabolized by glucuronidation.
GC66369 3-O-Methyltolcapone D7
Purity: >98%
3-O-Methyltolcapone D7 (Ro 40-7591 D7) is a deuterium labeled 3-O-Methyltolcapone. 3-O-Methyltolcapone is a metabolite of Tolcapone. Tolcapone is an orally active, reversible, selective and potent COMT inhibitor. Tolcapone crosses the blood-brain barrier, and can be used for treatment of Parkinson's disease.
GC71152 hMAO-B/MB-COMT-IN-1
CAS: 254974-70-4
Purity: >98.00%
hMAO-B/MB-COMT-IN-1 is a dual MAO-B/MB-COMT inhibitor (IC50s: 2.5 μΜ for hMAO-B, 3.84 μΜ for MB-COMT).

Category Product List
Catalog No.	Product Name	CAS No.	Purity
GC18091	Entacapone sodium salt	1047659-02-8	>98%
GC18091	COMT inhibitor
GC12535	Flopropione	2295-58-1	>98.50%
GC12535	5-HT receptor antagonist
GC14223	Nitecapone	116313-94-1	>99.00%
GC14223	S-COMT inhibitor
GC14843	Serotonin HCl	153-98-0	>98.00%
GC14843	Serotonin HCl a neurotransmitter, is a key messenger that mediates several central and peripheral functions in the human body.
GC17334	Entacapone	130929-57-6	>98.00%
GC17334	Entacapone is a potent, reversible, peripherally acting and orally active inhibitor of catechol-O-methyltransferase (COMT), which effectively inhibits rat liver total COMT with IC 50 and K i values of 20.1nM and 10.7nM, respectively.
GC17921	Tolcapone	134308-13-7	>98%
GC17921	A reversible COMT inhibitor
GC36811	Opicapone	923287-50-7	>99.50%
GC36811	A COMT inhibitor
GC62809	5-Hydroxyferulic acid	1782-55-4	>98%
GC62809	5-Hydroxyferulic acid is a hydroxycinnamic acid and is a metabolite of the phenylpropanoid pathway.
GC65175	Nebicapone	274925-86-9	>99.00%
GC65175	Nebicapone (BIA 3-202), a reversible catechol-O-methyltransferase (COMT) inhibitor, is mainly metabolized by glucuronidation.
GC66369	3-O-Methyltolcapone D7	-	>98%
GC66369	3-O-Methyltolcapone D7 (Ro 40-7591 D7) is a deuterium labeled 3-O-Methyltolcapone. 3-O-Methyltolcapone is a metabolite of Tolcapone. Tolcapone is an orally active, reversible, selective and potent COMT inhibitor. Tolcapone crosses the blood-brain barrier, and can be used for treatment of Parkinson's disease.
GC71152	hMAO-B/MB-COMT-IN-1	254974-70-4	>98.00%
GC71152	hMAO-B/MB-COMT-IN-1 is a dual MAO-B/MB-COMT inhibitor (IC50s: 2.5 μΜ for hMAO-B, 3.84 μΜ for MB-COMT).