GLPBio

CRBN ligand-896

Catalog No.: GC81009Purity:>98%
CRBN ligand-896 (CRBN-1) is a E3 ligase ligand of PROTAC that can be used to synthesize PROTAC degraders targeting the epigenetic coactivator p300 [1].

Products are for research use only. Not for human use. We do not sell to patients.


CRBN ligand-896
Cas No.: 2504234-93-7
100mgIn Stock
$165.00
1
250mgIn Stock
$322.00
1
500mgIn Stock
$472.00
1

Citations

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  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
  • Cell Research cover
    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

CRBN ligand-896 (CRBN-1) is a E3 ligase ligand of PROTAC that can be used to synthesize PROTAC degraders targeting the epigenetic coactivator p300 [1].

References:
[1]. Abbineni C, et al. Preparation of substituted heterocyclic compounds and their derivatives as CBP and/or p300 degraders. World Intellectual Property Organization, WO2025202979 A1 2025-10-02.

Chemical Properties

CAS No.
2504234-93-7
Molecular Formula
C16H11BrN2O3
Molecular Weight
359.17
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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