CRBN ligand-896 (CRBN-1) is a E3 ligase ligand of PROTAC that can be used to synthesize PROTAC degraders targeting the epigenetic coactivator p300 [1].
References:
[1]. Abbineni C, et al. Preparation of substituted heterocyclic compounds and their derivatives as CBP and/or p300 degraders. World Intellectual Property Organization, WO2025202979 A1 2025-10-02.
References:
[1]. Abbineni C, et al. Preparation of substituted heterocyclic compounds and their derivatives as CBP and/or p300 degraders. World Intellectual Property Organization, WO2025202979 A1 2025-10-02.
















