GLPBio

Cyclopropaneacetamide-Exatecan

Catalog No.: GC73669Purity:>97.00%
COASDSData Sheet
Cyclopropaneacetamide-Exatecan (Compound 2-A) is an ADC Cytotoxin and an Exatecan analogue.

Products are for research use only. Not for human use. We do not sell to patients.

Cyclopropaneacetamide-Exatecan
Cas No.: 2414254-36-5
5 mgIn Stock
$113.00
1
10 mgIn Stock
$180.00
1
25 mgIn Stock
$365.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    33, 546–561 (2023)
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    Cell Research
    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

Cyclopropaneacetamide-Exatecan (Compound 2-A) is an ADC Cytotoxin and an Exatecan analogue. Cyclopropaneacetamide-Exatecan can be used in the synthesis of ADC such as anti-B7H3 antibody-Exatecan analogue conjugate (compound ADC-2).

References:
[1]. Ying Hua, et al. Anti-b7h3 antibody-exatecan analog conjugate and medicinal use thereof. Patent WO2020063673A1.

Product Documents

Purity:>97.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
2414254-36-5
Molecular Formula
C29H28FN3O6
Molecular Weight
533.55
Solubility
DMSO : 100 mg/mL (187.42 mM; ultrasonic and warming and heat to 60°C)
Storage
-20°C, sealed storage, away from moisture and light
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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