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Home >> Signaling Pathways >> DNA Damage/DNA Repair >> Topoisomerase

Topoisomerase

Topoisomerase are enzymes that regulate the overwinding or underwinding of DNA.

Products for  Topoisomerase

  1. Cat.No. Product Name Information
  2. GC38194 (±)-10-Hydroxycamptothecin (±)-10-Hydroxycamptothecin is an indole alkaloid that inhibits the activity of topoisomerase I and has a broad spectrum of anticancer activity. (±)-10-Hydroxycamptothecin Chemical Structure
  3. GC73670 (αR)-Cyclopropaneacetamide-Exatecan (αR)-Cyclopropaneacetamide-Exatecan (compound 2-A), an Exenotecan derivative, is a cytotoxic agent. (αR)-Cyclopropaneacetamide-Exatecan Chemical Structure
  4. GC73057 (1R,9R)-Exatecan mesylate

    (1R,9R)-DX8951f

     (1R,9R)-Exatecan mesylate((1R,9R)-DX8951f) is an isomer of Exatecan mesylate. (1R,9R)-Exatecan mesylate Chemical Structure
  5. GC73056 (1S,9R)-Exatecan mesylate

    (1S,9R)-DX8951f

     (1S,9R)-Exatecan mesylate ((1S,9R)-DX8951f) is an isomer of Exatecan mesylate. (1S,9R)-Exatecan mesylate Chemical Structure
  6. GC74127 (R)-Exatecan Intermediate 1 (R)-Exatecan Intermediate 1 is an isomer of Exatecan Intermediate 1. (R)-Exatecan Intermediate 1 Chemical Structure
  7. GC10098 (S)-10-Hydroxycamptothecin

    ChEMBL 273862, NSC 107124

     inhibitor of topoisomerase I (S)-10-Hydroxycamptothecin Chemical Structure
  8. GC17271 4'-Demethylepipodophyllotoxin

    (-)-4′-Demethylepipodophyllotoxin

     An inhibitor of tubulin polymerization 4'-Demethylepipodophyllotoxin Chemical Structure
  9. GC41643 9(Z),11(E),13(E)-Octadecatrienoic Acid

    αEleostearic Acid, αESA, LAF 237

     9(Z),11(E),13(E)-Octadecatrienoic Acid (α-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. 9(Z),11(E),13(E)-Octadecatrienoic Acid Chemical Structure
  10. GC11903 9-amino Camptothecin

    NSC 603071

     9-amino Camptothecin (9-amino-20(S)-camptothecin) is a topoisomerase I inhibitor with potent anticancer activity. 9-amino Camptothecin Chemical Structure
  11. GC45367 9-Hydroxyellipticine (hydrochloride)

    9-OH-Ellipticine, NSC 210717

       9-Hydroxyellipticine (hydrochloride) Chemical Structure
  12. GN10035 9-Methoxycamptothecin 9-Methoxycamptothecin Chemical Structure
  13. GC74178 Ac-Exatecan Ac-Exatecan is acetylated Exatecan. Ac-Exatecan Chemical Structure
  14. GC35238 Aclacinomycin A hydrochloride

    Aclacinomycin A hydrochloride (Aclarubicin hydrochloride), a fluorescent molecule and the first described non-peptidic inhibitor showing discrete specificity for the CTRL (chymotrypsin-like) activity of the 20S proteasome. Aclacinomycin A hydrochloride is also a dual inhibitor of topoisomerase I and II. An effective anthracycline chemotherapeutic agent for hematologic cancers and solid tumors.

     Aclacinomycin A hydrochloride Chemical Structure
  15. GC49804 Acridine

    2,3,5,6-Dibenzopyridine, 10-Azaanthracene, Dibenzopyridine, NSC 3408

     An azaarene Acridine Chemical Structure
  16. GC14858 Aldoxorubicin

    INNO-206;Doxorubicin-EMCH;INNO 206

     An albumin-binding prodrug of doxorubicin Aldoxorubicin Chemical Structure
  17. GC10779 Alternariol

    AOH,NSC 638263

    A mycotoxin with antifungal and phytotoxic activity

     Alternariol Chemical Structure
  18. GC42783 Ametantrone

    NSC 196473, NSC 290813

     Ametantrone (NSC 196473) is an antitumor agent that intercalates into DNA and induces topoisomerase II (TOP2)-mediated DNA break. Ametantrone Chemical Structure
  19. GC11019 Amonafide

    AS1413, Benzisoquinolinedione, Nafidimide, NCI 308847, NSC 308847

     DNA intercalator,Topo II inhibitor Amonafide Chemical Structure
  20. GC15644 Amrubicin

    SM-5887

     A synthetic anthracycline antibiotic. It inhibits DNA topoisomerase II. Antineoplastic. Amrubicin Chemical Structure
  21. GC12326 Amsacrine Topoisomerase 2 inhibitor Amsacrine Chemical Structure
  22. GC11747 Amsacrine hydrochloride

    AMSA, m-AMSA, NSC 141549

     Topoisomerase 2 inhibitor Amsacrine hydrochloride Chemical Structure
  23. GC62425 ARN-21934 ARN-21934 is a potent, highly selective, blood-brain barrier (BBB) penetrant inhibitor for human topoisomerase II α over β. ARN-21934 inhibits DNA relaxation with an IC50 of 2 μM as compared to the anticancer agent Etoposide (IC50=120 μM). ARN-21934 exhibits a favorable in vivo pharmacokinetic profile and is a promising lead compound for anticancer research. ARN-21934 Chemical Structure
  24. GC46880 ARN24139 A topoisomerase II poison ARN24139 Chemical Structure
  25. GC39699 Aurintricarboxylic acid Aurintricarboxylic acid is a nanomolar-potency, allosteric antagonist with selectivity towards αβ-methylene-ATP-sensitive P2X1Rs and P2X3Rs, with IC50s of 8.6 nM and 72.9 nM for rP2X1R and rP2X3R, respectively. Aurintricarboxylic acid Chemical Structure
  26. GC33240 Banoxantrone D12 (AQ4N D12)

    AQ4N D12

     Banoxantrone D12 (AQ4N D12) is the deuterium labeled banoxantrone. Banoxantrone is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor. Banoxantrone D12 (AQ4N D12) Chemical Structure
  27. GC34169 Banoxantrone D12 dihydrochloride (AQ4N D12 dihydrochloride)

    AQ4N-d12 dihydrochloride

     Banoxantrone-d12 (AQ4N-d12) dihydrochloride is the deuterium labeled Banoxantrone dihydrochloride. Banoxantrone is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor. Banoxantrone D12 dihydrochloride (AQ4N D12 dihydrochloride) Chemical Structure
  28. GC34085 Banoxantrone dihydrochloride (AQ4N dihydrochloride)

    AQ4N dihydrochloride

     Banoxantrone dihydrochloride (AQ4N dihydrochloride) is an oxygen-depleted activated topoisomerase II inhibitor, AQ4N binds to DNA in a non-covalent manner and promotes antitumor activity of hypoxic and hypoxic tumor cells. Banoxantrone dihydrochloride (AQ4N dihydrochloride) Chemical Structure
  29. GC42912 Becatecarin

    BMS 181176, BMY 27557, NSC 655649, XL 119

     Becatecarin is a water-soluble, diethylaminoethyl analog of the antineoplastic antibiotic rebeccamycin. Becatecarin Chemical Structure
  30. GC33066 Belotecan hydrochloride (CKD-602)

    7-2-(N-isopropylamino)ethyl-(20S)-Camptothecin, CKD602, (S)-CKD602

     Belotecan hydrochloride (CKD-602) (CKD-602 hydrochloride), a Topoisomerase I inhibitor, is a synthetic camptothecin derivative. Belotecan hydrochloride (CKD-602) Chemical Structure
  31. GN10221 Berberine

    Berberine (Natural Yellow 18) is an alkaloid isolated from the Chinese herbal medicine Huanglian, as an antibiotic. Berberine (Natural Yellow 18) induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase.

     Berberine Chemical Structure
  32. GC35497 Berberine chloride hydrate Berberine chloride hydrate (Natural Yellow 18 chloride hydrate) is an alkaloid that acts as an antibiotic. Berberine chloride hydrate induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties. Berberine chloride hydrate Chemical Structure
  33. GN10208 Berberine hydrochloride

    BBR, Umbellatine, NSC 163088, NSC 646666

     Berberine hydrochloride is a bioactive alkaloid of the isoquinoline class derived from the medicinal plant Coptis chinensis of the Ranunculaceae family, possessing a wide range of pharmacological functions with applications in cancer, inflammation, diabetes, depression, hypertension, and various infections. Berberine hydrochloride Chemical Structure
  34. GN10523 Berberine Sulfate Berberine Sulfate Chemical Structure
  35. GC10734 Beta-Lapachone

    ARQ 501, NSC 26326, NSC 629749, SL 11001

     Beta-Lapachone (ARQ-501;NSC-26326) is a naturally occurring O-naphthoquinone, acts as a topoisomerase I inhibitor, and induces apoptosis by inhibiting cell cycle progression. Beta-Lapachone Chemical Structure
  36. GC10480 Betulinic acid

    Lupatic Acid, NSC 113090

     Betulinic acid is a natural pentacyclic triterpenoid compound and an inhibitor of eukaryotic topoisomerase I with an IC50 value of 5 μM. Betulinic acid Chemical Structure
  37. GC19073 Bisantrene Bisantrene is a highly effective antitumor drug, targets eukaryotic type II topoisomerases. Bisantrene Chemical Structure
  38. GC68772 Bisantrene dihydrochloride

    CL-216942 dihydrochloride

    Bisantrene dihydrochloride is an effective anticancer agent that exerts cytotoxicity by affecting DNA intercalation. Bisantrene dihydrochloride targets the topoisomerase II of eukaryotes. Bisantrene dihydrochloride is a substrate for MDR1.

     Bisantrene dihydrochloride Chemical Structure
  39. GC73205 Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT (Formula V) is a agent-linker conjugate that composed of a potent topoisomerase I inhibitor and a linker to make antibody agent conjugate (ADC). Br-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT Chemical Structure
  40. GC15439 Camptothecin

    MAGCPT, NSC 94600

     Camptothecin is a specific DNA topoisomerase I (Top1) inhibitor with an IC50 value of 679 nM. Camptothecin Chemical Structure
  41. GC60669 Camptothecin-20(S)-O-propionate

    Camptothecin-20-O-propionate

     Camptothecin-20(S)-O-propionate (CZ48), the C20-propionate ester of CPT, is a highly effective anticancer agent. Camptothecin-20(S)-O-propionate (CZ48) is a topoisomerase-Ι inhibitor. Camptothecin-20(S)-O-propionate Chemical Structure
  42. GC46113 CAY10744 A topoisomerase II-α poison CAY10744 Chemical Structure
  43. GC73843 CB07-Exatecan CB07-Exatecan is an ADC drug-Linker conjugate that can be used for the synthesis of ADCs. CB07-Exatecan Chemical Structure
  44. GC60692 CH-0793076 TFA

    TP3076 TFA

     CH-0793076 (TP3076) TFA, a hexacyclic camptothecin analog, is active drug and major metabolite of TP300. CH-0793076 TFA inhibits DNA topoisomerase I with an IC50 of 2.3 μM. CH-0793076 TFA is efficacious against cells expressing BCRP (breast cancer resistance protein). CH-0793076 TFA Chemical Structure
  45. GC18536 Chartreusin

    Antibiotic X 465A, Lambdamycin, NSC 5159

     Chartreusin is an antibiotic originally isolated from S. Chartreusin Chemical Structure
  46. GC72859 Chimmitecan

    (S)-9-Allyl-10-Hydroxycamptothecin

     Chimmitecan ((S)-9-Allyl-10-droxycamptothecin), a novel 9-small-alkyl-substituted lipophilic Camptothecin , is a potent inhibitor of topoisomerase I. Chimmitecan Chemical Structure
  47. GC60107 Chloroquinoxaline sulfonamide Chloroquinoxaline sulfonamide (Chloroquinoxaline), a structural analogue of sulfaquinoxaline, is a topoisomerase II alpha/beta poison. Chloroquinoxaline sulfonamide Chemical Structure
  48. GC50105 CKD 602 Topoisomerase I inhibitor CKD 602 Chemical Structure
  49. GC47098 CL2-SN-38 (dichloroacetic acid salt) An antibody-drug conjugate containing SN-38 CL2-SN-38 (dichloroacetic acid salt) Chemical Structure
  50. GC60714 CL2A-SN-38 An antibody-drug conjugate containing SN-38 CL2A-SN-38 Chemical Structure
  51. GC61965 Coralyne chloride Coralyne chloride is a protoberberine alkaloid with potent anti-cancer activities. Coralyne chloride acts as a potent topoisomerase I poison and induces Top I mediated DNA cleavage. Coralyne chloride can be used for preparing?coralyne derivatives?as DNA binding fluorescent probes. Coralyne chloride Chemical Structure
  52. GC73634 Cu(II)-Elesclomol Cu(II)-Elesclomol is a Cu2+ complex of Elesclomol. Cu(II)-Elesclomol Chemical Structure
  53. GC73746 Cyclooctyne-O-amido-PEG4-VC-PAB-Gly-Gly-NH-O-CO-Exatecan Cyclooctyne-O-amido-PEG4-VC-PAB-Gly-Gly-NH-O-CO-Exatecan is a drug-linker conjugate for ADC (ADC Cytotoxin: Exatecan). Cyclooctyne-O-amido-PEG4-VC-PAB-Gly-Gly-NH-O-CO-Exatecan Chemical Structure
  54. GC73669 Cyclopropaneacetamide-Exatecan Cyclopropaneacetamide-Exatecan (Compound 2-A) is an ADC Cytotoxin and an Exatecan analogue. Cyclopropaneacetamide-Exatecan Chemical Structure
  55. GC73079 Datopotamab deruxtecan

    DS-1062; Dato-DXd

     Datopotamab deruxtecan (DS-1062; Dato-DXd) is a trophoblast cell surface antigen 2 (TROP2)-directed antibody-drug conjugate (ADC). Datopotamab deruxtecan Chemical Structure
  56. GC11175 Daun02 Daun02 Chemical Structure
  57. GC12828 Daunorubicin

    DNA topoisomerase II inhibitor

     Daunorubicin Chemical Structure
  58. GC10354 Daunorubicin HCl

    NDC 00824155, Ondena, RP 13057

     Daunorubicin (Daunomycin) hydrochloride is a topoisomerase II inhibitor with potent anti-tumor activity. Daunorubicin HCl Chemical Structure
  59. GC73899 DBCO-β-Glu-PEG12-Exatecan DBCO-β-Glu-PEG12-Exatecan (Compound 107) is an inhibitor for topoisomerase I. DBCO-β-Glu-PEG12-Exatecan Chemical Structure
  60. GC73419 Decyclohexanamine-Exatecan Decyclohexanamine-Exatecan is a Camptothecin derivative, compound a, extracted from patent WO2020219287 A1. Decyclohexanamine-Exatecan Chemical Structure
  61. GC17412 Deferasirox Fe3+ chelate Deferasirox Fe3+ chelate Chemical Structure
  62. GC11619 Dexrazoxane HCl (ICRF-187, ADR-529) Topoisomerase II inhibitor,intracellular ion chelator,cardioprotective agent Dexrazoxane HCl (ICRF-187, ADR-529) Chemical Structure
  63. GC15250 DOXO-EMCH

    INNO-206;Doxorubicin-EMCH;INNO 206

     Prodrug of doxorubicin DOXO-EMCH Chemical Structure
  64. GC17567 Doxorubicin (Adriamycin) HCl

    DOX

     Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin (Adriamycin) HCl Chemical Structure
  65. GC15399 Dp44mT iron chelator and anticancer agent Dp44mT Chemical Structure
  66. GC38774 DRF-1042 DRF-1042 is an orally active derivative of Camptothecin. DRF-1042 acts to inhibit DNA topoisomerase I. DRF-1042 shows good anticancer activity against a panel of human cancer cell lines including multi-drug resistance (MDR) phenotype. DRF-1042 Chemical Structure
  67. GC32926 Dxd (Exatecan derivative) DXd is a derivative of Exatecan (DX-8951). Dxd (Exatecan derivative) Chemical Structure
  68. GC62212 Dxd-D5

    Exatecan-d5 derivative for ADC

     Dxd-d5 (Exatecan-d5 derivative for ADC) is a deuterium labeled Dxd. Dxd is a potent DNA topoisomerase I inhibitor, with an IC50 of 0.31 μM, used as a conjugated drug of HER2-targeting ADC (DS-8201a) . Dxd-D5 Chemical Structure
  69. GC33128 Edotecarin (J 107088)

    J 107088; PF 804950

     Edotecarin (J 107088) is a potent inhibitor of topoisomerase I that can induces single-strand DNA cleavage, with IC50 of 50 nM. Edotecarin (J 107088) Chemical Structure
  70. GC18620 EIDD-1931

    β-D-N4-Hydroxycytidine, N4-Hydroxycytidine

    A ribonucleoside analog with antiviral activity

     EIDD-1931 Chemical Structure
  71. GC15548 Ellagic acid

    Gallogen, Lagistase, TBBD

     Casein kinase 2 (CK2) inhibitor Ellagic acid Chemical Structure
  72. GC15305 Ellipticine DNA topoisomerase II inhibitor Ellipticine Chemical Structure
  73. GC35973 Ellipticine hydrochloride Ellipticine (NSC 71795) hydrochloride is a potent antineoplastic agent; inhibits DNA topoisomerase II activities. Ellipticine hydrochloride Chemical Structure
  74. GC35997 Epirubicin Epirubicin (4'-Epidoxorubicin), a semisynthetic L-arabino derivative of doxorubicin, has an antineoplastic agent by inhibiting Topoisomerase. Epirubicin inhibits DNA and RNA synthesis. Epirubicin is a Forkhead box protein p3 (Foxp3) inhibitor and inhibits regulatory T cell activity. Epirubicin Chemical Structure
  75. GC10686 Epirubicin HCl

    4’Epidoxorubicin

     Epirubicin HCl (4'-Epidoxorubicin hydrochloride), a semisynthetic L-arabino derivative of doxorubicin, has an antineoplastic agent by inhibiting Topoisomerase. Epirubicin HCl inhibits DNA and RNA synthesis. Epirubicin HCl is a Forkhead box protein p3 (Foxp3) inhibitor and inhibits regulatory T cell activity. Epirubicin HCl Chemical Structure
  76. GC15617 Etoposide

    VP-16; VP-16-213

     Etoposide (VP-16) is a nonspecific inhibitor of topoisomerase II with an IC50 value of 59.2μM. Etoposide Chemical Structure
  77. GC60826 Etoposide phosphate Etoposide phosphate (BMY-40481) is a potent anti-cancer chemotherapy agent and a selective topoisomerase II inhibitor?to prevent re-ligation of DNA strands. Etoposide phosphate Chemical Structure
  78. GC33108 Exatecan (DX-8951) Exatecan (DX-8951) is a nonprodrug camptothecin (CPT) derivative, exhibits significant topoisomerase I inhibition. Exatecan (DX-8951) Chemical Structure
  79. GC74150 Exatecan analog 36 Exatecan analog 36 is a analog of Exatecan. Exatecan analog 36 Chemical Structure
  80. GC62184 Exatecan D5 mesylate

    DX8951f-d5; Exatecan-d5 mesylate; Deuterated labeled Exatecan mesylate

     Exatecan D5 mesylate Chemical Structure
  81. GC74652 Exatecan Intermediate 2 hydrochloride Exatecan Intermediate 2 drochloride (compound B) is an intermediate of Exatecan (DX-8951, ). Exatecan Intermediate 2 hydrochloride Chemical Structure
  82. GC74653 Exatecan Intermediate 4 Exatecan Intermediate 4 (compound B) is an intermediate of Exatecan (DX-8951, ). Exatecan Intermediate 4 Chemical Structure
  83. GC74654 Exatecan Intermediate 4 dihydrochloride Exatecan Intermediate 4 didrochloride is an intermediate of Exatecan (DX-8951, ). Exatecan Intermediate 4 dihydrochloride Chemical Structure
  84. GC74132 Exatecan Intermediate 5 Exatecan Intermediate 5 is the intermediate of Exatecan And Exatecan (DX-8951) is a DNA topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL) that can be used in cancer research. Exatecan Intermediate 5 Chemical Structure
  85. GC74134 Exatecan Intermediate 6 Exatecan Intermediate 6 is the intermediate of Exatecan And Exatecan (DX-8951) is a DNA topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL) that can be used in cancer research. Exatecan Intermediate 6 Chemical Structure
  86. GC74135 Exatecan Intermediate 7 Exatecan Intermediate 7 is the intermediate of Exatecan And Exatecan (DX-8951) is a DNA topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL) that can be used in cancer research. Exatecan Intermediate 7 Chemical Structure
  87. GC19148 Exatecan Mesylate

    DX 8951f

     Exatecan Mesylate is a water soluble topoisomerase I inhibitor, with an IC50 of 2.2 uM (0.975 ug/mL), and can be used in cancer research. Exatecan Mesylate Chemical Structure
  88. GC73711 Exatecan-methylacetamide-OH Exatecan-metlacetamide-OH (compound 6) is a Exatecan derivative with anticancer effects. Exatecan-methylacetamide-OH Chemical Structure
  89. GC16455 Flumequine

    (±)-Flumequine, R-802

     DNA topoisomerase II inhibitor，synthetic chemotherapeutic antibiotic Flumequine Chemical Structure
  90. GC49134 Flumequine-13C3

    (±)-Flumequine-13C3, R-802-13C3

     An internal standard for the quantification of flumequine Flumequine-13C3 Chemical Structure
  91. GC70215 Fmoc-leucine-15N Fmoc-leucine-15N is a 15N-labeled and 13C-labled EIDD-1931. Fmoc-leucine-15N Chemical Structure
  92. GC14376 Gatifloxacin

    AM1155, BMS 20658401, PD 135432

     Fluoroquinolone antibiotic,inhibits bacterial TOPO II Gatifloxacin Chemical Structure
  93. GC14102 Genistein

    CI-75610, NSC 36586

     Genistein is an isoflavone belonging to the flavonoid group of compounds and is found in a number of plants. Genistein Chemical Structure
  94. GC15853 Genz-644282

    Genz644282;Genz 644282

     An inhibitor of topoisomerase I Genz-644282 Chemical Structure
  95. GC32088 Gepotidacin (GSK2140944)

    GSK2140944

     Gepotidacin (GSK2140944) (GSK2140944) is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor. Gepotidacin (GSK2140944) Chemical Structure
  96. GC73458 GGFG-amide-glycol-amide-Exatecan GGFG-amide-glycol-amide-Exatecan (Intermediate 2) is an Exatecan derivative and can be used in the synthesis of antibody-drug conjugates (ADCs). GGFG-amide-glycol-amide-Exatecan Chemical Structure
  97. GC60873 Gimatecan

    ST1481

     Gimatecan (ST1481) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity. Gimatecan Chemical Structure
  98. GC73055 Gly-Gly-Phe-Gly-NH-O-CO-Exatecan hydrochloride Gly-Gly-Phe-Gly-NH-O-CO-Exatecan, as a drug-linker conjugate composed of linker Gly-Gly-Phe-Gly-NH-O-CO and Exatecan, can be used to prepare antibody conjugate drugs. Gly-Gly-Phe-Gly-NH-O-CO-Exatecan hydrochloride Chemical Structure
  99. GC73503 Gly-Mal-GGFG-Deruxtecan 2-hydroxypropanamide Gly-Mal-GGFG-Deruxtecan 2-droxy propionamide is a camptothecin-deriver and can be used as a drug linker for ADC. Gly-Mal-GGFG-Deruxtecan 2-hydroxypropanamide Chemical Structure
  100. GC38511 Groenlandicine Groenlandicine is a protoberberine alkaloid isolated from Coptidis Rhizoma. Groenlandicine Chemical Structure
  101. GC14969 Idarubicin HCl

    4Demethoxydaunorubicin, 4DMD, NSC 256439

     Idarubicin HCl is an anthracycline antileukemic drug. Idarubicin HCl Chemical Structure

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