Acetyl-6-formylpterin (Synonyms: Ac-6-FP, 2-Acetamido-6-formylpteridin-4-one, NSC 129965) |
| Katalog-Nr.GC18443 |
Acetyl-6-formylpterin is an inhibitor of mucosal-associated invariant T (MAIT) cell activation.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 29769-49-1
Sample solution is provided at 25 µL, 10mM.
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Acetyl-6-formylpterin is an inhibitor of mucosal-associated invariant T (MAIT) cell activation. It dose-dependently increases the surface expression of MHC-related 1 (Mr1) in WT3 cells overexpressing Mr1 (WT3-m) following incubation with E. coli but does not activate MAIT cells cocultured with WT3-m cells when used at concentrations ranging from 0.23-15 uM. Acetyl-6-formylpterin is also a degradation product of folic acid and a precursor in the synthesis of 2'-hydroxy-7,8-dihydrofolate, which is a metabolite of para-aminosalicylic acid (PAS) in M. tuberculosis.
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Average Rating: 5 (Based on Reviews and 38 reference(s) in Google Scholar.)
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