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| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 10mM (in 1mL DMSO) | $140.00 | In Stock | 1 | |
| 5mg | $135.00 | In Stock | 1 | |
| 10mg | $216.00 | In Stock | 1 | |
| 25mg | $441.00 | In Stock | 1 |
AGL-2263 is an insulin receptor (IR) blocker.
AGL-2263 is an insulin receptor (IR) blocker[1].
[1]. Li Y, et al. GDM-associated insulin deficiency hinders the dissociation of SERT from ERp44 and down-regulates placental 5-HT uptake. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):E5697-705.
Cell experiment: | Trophoblast cells are prepared from normal or GDM placentas. They are incubated in the presence of stimulants, insulin (100 nM) or both insulin and AGL-2263 (AGL, 5 μM) IR blocker, together for 24 hr[1]. |
References: [1]. Li Y, et al. GDM-associated insulin deficiency hinders the dissociation of SERT from ERp44 and down-regulates placental 5-HT uptake. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):E5697-705. | |