GLPBio

ANO1-IN-4

Catalog No.: GC82195Purity:>99.50%
COASDSData Sheet
ANO1-IN-4 (Compound 10bm) is a reversible inhibitor for calcium-activated chloride channel transmembrane protein 16A ( TMEM16A, also known as ANO1 ) with an IC50 of 0.030 µM.

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ANO1-IN-4
Cas No.: 2098490-06-1
10mM (in 1mL DMSO)In Stock
$294.00
1
1mgIn Stock
$117.00
1
5mgIn Stock
$293.00
1
10mgIn Stock
$468.00
1
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Zitate (Citations)

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    641, 529–536 (2025)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    387(6734) (2025)
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    35, 97–116 (2025)
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Beschreibung (Description)

ANO1-IN-4 (Compound 10bm) is a reversible inhibitor for calcium-activated chloride channel transmembrane protein 16A ( TMEM16A, also known as ANO1 ) with an IC50 of 0.030 µM. ANO1-IN-4 exhibits good metabolic stability in rat liver microsomes. ANO1-IN-4 inhibits spontaneous contraction in mouse isolated ileum [1].

References:
[1]. Truong EC, et al., Substituted 2-Acylaminocycloalkylthiophene-3-carboxylic Acid Arylamides as Inhibitors of the Calcium-Activated Chloride Channel Transmembrane Protein 16A (TMEM16A). J Med Chem. 2017 Jun 8;60(11):4626-4635.

Produktdokumente (Product Documents)

Purity:>99.50%Appearance:A solid
COASDSData Sheet

Chemische Eigenschaften (Chemical Properties)

CAS-Nr.
2098490-06-1
Summenformel
C19H19BrF2N2O2S
Molekulargewicht
457.33
Löslichkeit
DMSO: 50 mg/mL (109.33 mM; Need ultrasonic)
Lagerung
Store at -20°C
Versandbedingungen
Evaluierungsmuster werden mit Kühlakkus versandt. Andere verfügbare Größen werden bei Raumtemperatur oder auf Anfrage mit Kühlakkus versandt.

Rechner (Calculators)Molarität / Verdünnung / Molekulargewicht / Einheitenumrechnung / In-vivo-Formulierung / Löslichkeit

g/mol

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