BTA-1_b (Synonyms: BTA-1-CH3) |
Katalog-Nr.GC79788
One-Click Copy Product Info
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BTA-1 _b (BTA-1-CH3) is a structural analog of BTA-1.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 95856-73-8
Sample solution is provided at 25 µL, 10mM.
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In Vitro, Structural analogs are frequently used as control compounds to distinguish whether the biological effects of a target molecule are mediated by specific target binding or by non-specific physicochemical properties.
References:
[1]. Tomoshige S, et al. Discovery of Small Molecules that Induce the Degradation of Huntingtin. Angew Chem Int Ed Engl. 2017 Sep 11;56(38):11530-11533.
[2]. Wu C, et. al. The binding of thioflavin T and its neutral analog BTA-1 to protofibrils of the Alzheimer's disease Abeta(16-22) peptide probed by molecular dynamics simulations. J Mol Biol. 2008 Dec 19;384(3):718-29.
| Cas No. | 95856-73-8 | SDF | |
| Überlieferungen | BTA-1-CH3 | ||
| Formula | C15H14N2S | M.Wt | 254.35 |
| Löslichkeit | DMSO: 5.56 mg/mL (21.86 mM; ultrasonic and warming and heat to 60°C) | Storage | Store at -20°C |
| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 3.9316 mL | 19.658 mL | 39.3159 mL |
| 5 mM | 786.3 μL | 3.9316 mL | 7.8632 mL |
| 10 mM | 393.2 μL | 1.9658 mL | 3.9316 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >98.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)