C-Kit-IN-16 is a c-kit inhibitor with an IC50 of 25 nM. C-Kit-IN-16 can be used in the research of acute megakaryocytic leukemia [1].
In Vitro, C-Kit-IN-16 (Compound 109) (3 days) inhibits the proliferation of M-07e cells, with its IC50 being 12 nM[1].
References:
[1]. Taisuke Takahashi, et al. Kit inhibitors, compounds, pharmaceutical compositions, and methods of use thereof. WO2024029489.
In Vitro, C-Kit-IN-16 (Compound 109) (3 days) inhibits the proliferation of M-07e cells, with its IC50 being 12 nM[1].
References:
[1]. Taisuke Takahashi, et al. Kit inhibitors, compounds, pharmaceutical compositions, and methods of use thereof. WO2024029489.