DSPE-PEG2000-VHPKQHRGGSKGC is a targeted modified phospholipid-polyethylene glycol conjugate covalently coupled to DSPE, PEG, and the vascular-targeting peptide VHPKQHRGGSKGC. DSPE-PEG2000-VHPKQHRGGSKGC can be used for research on tumor vascular imaging and vascular-targeted drug delivery.
In Vitro, Lipids used to prepare nanoparticles are a class of amphiphilic biomolecules that combine structural diversity, biocompatibility, and functional tunability. As the core framework of nanodelivery systems, they not only form lipid bilayers or solid matrices through self-assembly to encapsulate lipophilic or hydrophilic drugs, but can also be further subdivided according to formulation requirements into structural lipids (such as phospholipids and triglycerides), functional lipids (such as ionizable cationic lipids used for nucleic acid condensation and endosome escape), and sterically stable lipids (such as PEGylated lipids).
References:
[1]. Fu Y, et al. Endocytic pathway of vascular cell adhesion molecule 1 in human umbilical vein endothelial cell identified in vitro by using functionalized nontoxic fluorescent quantum dots. Sensors and Actuators B: Chemical, 2019, 297: 126702.
In Vitro, Lipids used to prepare nanoparticles are a class of amphiphilic biomolecules that combine structural diversity, biocompatibility, and functional tunability. As the core framework of nanodelivery systems, they not only form lipid bilayers or solid matrices through self-assembly to encapsulate lipophilic or hydrophilic drugs, but can also be further subdivided according to formulation requirements into structural lipids (such as phospholipids and triglycerides), functional lipids (such as ionizable cationic lipids used for nucleic acid condensation and endosome escape), and sterically stable lipids (such as PEGylated lipids).
References:
[1]. Fu Y, et al. Endocytic pathway of vascular cell adhesion molecule 1 in human umbilical vein endothelial cell identified in vitro by using functionalized nontoxic fluorescent quantum dots. Sensors and Actuators B: Chemical, 2019, 297: 126702.