Startseite>>Signaling Pathways>> GPCR/G protein>> CCR>>ECL1i TFA

ECL1i TFA

Katalog-Nr.GC79218 Copy One-Click Copy Product Info

ECL1i TFA is an allosteric, selective CCR2 inhibitor.

Products are for research use only. Not for human use. We do not sell to patients.

ECL1i TFA Chemische Struktur

Größe Preis Lagerbestand Menge
5mg
81,00 $
Auf Lager
10mg
134,00 $
Auf Lager
25mg
267,00 $
Auf Lager

Tel:(909) 407-4943 Email: sales@glpbio.com


Kundenbewertungen

Basiert auf Kundenrezensionen.

Sample solution is provided at 25 µL, 10mM.



Description of ECL1i TFA

ECL1i TFA is an allosteric, selective CCR2 inhibitor. ECL1i TFA specifically inhibits CCL2-/CCR2-mediated chemotaxis. ECL1i TFA interferes with CCR2-positive cell recruitment and attenuates disease progression in experimental autoimmune encephalomyelitis [1].

References:
[1]. Auvynet C, et al. ECL1i, d(LGTFLKC), a novel, small peptide that specifically inhibits CCL2-dependent migration. FASEB J. 2016 Jun;30(6):2370-81. doi: 10.1096/fj.201500116. Epub 2016 Mar 15. Erratum in: FASEB J. 2017 Feb;31(2):852.

Chemical Properties of ECL1i TFA

Cas No. SDF
Formula C38H61F3N8O11S M.Wt 895
Löslichkeit Storage Sealed storage, away from moisture
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of ECL1i TFA

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.1173 mL 5.5866 mL 11.1732 mL
5 mM 223.5 μL 1.1173 mL 2.2346 mL
10 mM 111.7 μL 558.7 μL 1.1173 mL
  • Molaritätsrechner

  • Verdünnung-Rechner

  • Molecular Weight Calculator

Gewicht
=
Konzentration
x
Inhalt
x
MW*
 
 
 
**Bei der Herstellung von Stammlösungen ist immer das chargenspezifische Molekulargewicht von

Berechnen

In vivo Formulation Calculator (Clear solution) of ECL1i TFA

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

View current batch:

Bewertungen

Review for ECL1i TFA

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%