Phillyrin (Forsythin) |
| Katalog-Nr.GC38421 |
Phillyrin (Forsythin) wird aus Forsythia suspensa Vahl (Oleaceae) isoliert und wirkt antibakteriell und entzÜndungshemmend.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 487-41-2
Sample solution is provided at 25 µL, 10mM.
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Phillyrin is isolated from Forsythia suspensa Vahl (Oleaceae), has antibacterial and anti-inflammatory activities. Phillyrin has potential inductive effects on rat CYP1A2 and CYP2D1 activities, without affecting CYP2C11 and CYP3A1/2 activities[1].
Phillyrin (1-5 μM; pretreatment 1 hour; 24 hours) inhibits high glucose-induced FAS protein significantly in HepG2 cells[1].Phillyrin (1-5 μM; pretreatment 1 hour; 24 hours) inhibits high glucose-induced FAS mRNA expression by suppressing SREBP-1c activation in human HepG2 hepatocytes[1]. RT-PCR[1] Cell Line: Human HepG2 hepatocyte cells
[1]. Cheng Y, et al. Effects of phillyrin and forsythoside A on rat cytochrome P450 activities in vivo and in vitro. Xenobiotica. 2017 Apr;47(4):297-303. [2]. Do MT, et al. Phillyrin attenuates high glucose-induced lipid accumulation in human HepG2 hepatocytes through the activation of LKB1/AMP-activated protein kinase-dependent signalling. Food Chem. 2013 Jan 15;136(2):415-25.
Average Rating: 5 (Based on Reviews and 19 reference(s) in Google Scholar.)
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