1,6-Diphenyl-1,3,5-hexatriene (Synonyms: Diphenylhexatriene, DPH, NSC 90479) |
| Katalog-Nr.GC45306 |
1,6-Diphenyl-1,3,5-hexatrien ist eine fluoreszierende Sonde.
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Cas No.: 1720-32-7
Sample solution is provided at 25 µL, 10mM.
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1,6-Diphenyl-1,3,5-hexatriene is a probe for lipid mono- and bilayers.1,2,3 It localizes to the hydrocarbon regions in lipid mono- and bilayers and displays excitation/emission maxima of 360/430 nm, respectively.1,2 1,6-Diphenyl-1,3,5-hexatriene has been used to characterize lipid membrane dynamics in vitro and ex vivo and in the determination of the critical micelle concentrations (CMCs) of anionic, cationic, uncharged, and zwitterionic detergents.1,2,3
References
1. Chattopadhyay, A., and London, E. Fluorimetric determination of critical micelle concentration avoiding interference from detergent charge. Anal. Biochem. 139(2), 408-412 (1984).
2. Tang, D., Wieb van der Meer, B., and Simon Chen, S.-Y. Evidence for a regular distribution of cholesterol in phospholipid bilayers from diphenylhexatriene fluorescence. Biophys J. 68(5), 1944-1951 (1995).
3. Cohen, B.M., and Zubenko, G.S. In vivo effects of psychotropic agents on the physical properties of cell membranes in the rat brain. Psychopharmacology (Berl) 86(3), 365-368 (1985).
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