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IRFI-165

Katalog-Nr.GC79190 Copy One-Click Copy Product Info

IRFI-165 is a potent and selective A 1 adenosine receptor antagonist with a K i of 7.9 nM for rat A 1 AR.

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IRFI-165 Chemische Struktur

Cas No.: 191349-26-5

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5mg
61,00 $
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10mg
98,00 $
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25mg
174,00 $
Auf Lager
50mg
279,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.



Description of IRFI-165

IRFI-165 is a potent and selective A 1 adenosine receptor antagonist with a K i of 7.9 nM for rat A 1 AR. IRFI-165 exhibies high selectivity versus A 2A and A 3 receptors. IRFI-165 induces antidepressant activity in vivo. IRFI-165 can be used for the research of psychiatric and neurological disorders [1].

References:
[1]. Hess S. Recent advances in adenosine receptor antagonist research. Expert Opinion on Therapeutic Patents, 2001, 11(10): 1533-1561.

Chemical Properties of IRFI-165

Cas No. 191349-26-5 SDF
Formula C16H18N4 M.Wt 266.35
Löslichkeit DMSO: 12.5 mg/mL (46.93 mM; ultrasonic and warming and heat to 60°C) Storage Store at -20°C
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of IRFI-165

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1 mg 5 mg 10 mg
1 mM 3.7545 mL 18.7723 mL 37.5446 mL
5 mM 750.9 μL 3.7545 mL 7.5089 mL
10 mM 375.4 μL 1.8772 mL 3.7545 mL
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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