MS7972 |
| Katalog-Nr.GC62322 |
MS7972 ist ein kleines MolekÜl, das die Assoziation von humanem p53 und CREB-Bindungsprotein blockiert. MS7972 kann diese BRD-Interaktion bei 50 μ fast vollstÄndig blockieren;M.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 352553-42-5
Sample solution is provided at 25 µL, 10mM.
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MS7972 is a small molecule that blocks human p53 and CREB binding protein association. MS7972 can almost completely block this BRD interaction at 50 μM[1].
Addition of MS7972 to the CBP BRD results in emission at 445 nm and quenching of the CBP BRD due to resonance energy transfer[1].
[1]. Sachchidanand, et al. Target structure-based discovery of small molecules that block human p53 and CREB binding protein association. Chem Biol. 2006 Jan;13(1):81-90.
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