Naled is an organophosphate insecticide and acaricide that inhibits acetylcholinesterase (AChE) and butyrylcholinesterase (BChE).1 It reduces the number of A. sollicitans mosquitos by 97% after one hour when aerially applied at a concentration of 0.1 pounds per acre.2 Naled (125 ppm AI) induces 100 and 64% mortality of T. telarius adults and immature mites, respectively, in an immediate contact toxicity test but does not induce mortality in mite eggs.3 It is toxic to rats with an LD50 value of 250 mg/kg.4 Formulations containing naled have been used in the control of mosquitoes in public areas and of crop-damaging insects in agriculture.
1.Herzsprung, P., Weil, L., and Niessner, R.Measurement of bimolecular rate constants ki of the cholinesterase inactivation reaction by 55 insecticides and of the influence of various pyridiniumoximes on kiInt. J. Eniviron. Anal. Chem.47(3)181-200(1992) 2.Knapp, F.W., and Rogers, C.E.Low volume aerial insecticide application for the control of Aedes sollicit and walkerMosquito News28(4)535-540(1968) 3.Mailloux, M., and Morrison, F.O.The effects of acaricides on the developmental stages of the two-spotted spider mite, Tetranychu telariusJ. Econ. Entomol.55(4)479-483(1962) 4.Gaines, T.B.Acute toxicity of pesticidesToxicol. Appl. Pharmacol.14(3)515-534(1969)