Nilutamide (Synonyms: RU-23908) |
| Katalog-Nr.GC44405 |
Nilutamid (Nilandron) ist ein oral wirksamer nichtsteroidaler Androgenrezeptorantagonist mit AffinitÄt zu Androgenrezeptoren, aber nicht zu Gestagen-, Östrogen- oder Glukokortikoidrezeptoren.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 63612-50-0
Sample solution is provided at 25 µL, 10mM.
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Nilutamide is a non-steroidal antiandrogen that is an antagonist of the androgen receptor. It reverses testosterone-induced increases in cell proliferation with an IC50 value of 412 nM in mouse mammary carcinoma cells in vitro. It has antiandrogenic activity in both intact and castrated rats, inhibiting testosterone propionate-induced prostate growth when administered at a dose of 2.5 mg/kg. Formulations containing nilutamide have been used in combination with surgical castration in the treatment of metastatic prostate cancer.
Average Rating: 5 (Based on Reviews and 32 reference(s) in Google Scholar.)
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