Oxathiapiprolin

Oxathiapiprolin is an anti-phytopathogenic oomycete agent. Oxathiapiprolin inhibits mycelial growth, sporangium production, zoospore release and zoospore motility in specific oomycetes. Oxathiapiprolin exhibits both protective and therapeutic activities against Phytophthora capsici infection in pepper plants. Oxathiapiprolin can be used in studies related to plant diseases ^[1].

In Vivo, Oxathiapiprolin (20-30 g/ha; foliar spray) exhibits dose-dependent protective and curative activities against Phytophthora blight of pepper under greenhouse conditions^[1]. Oxathiapiprolin (20-40 g active ingredient per hectare; spray application; 2 applications per growing season) exhibits a dose-dependent control efficacy against naturally occurring Phytophthora blight of pepper under field conditions^[1].

In Vitro, Oxathiapiprolin (0-5 days) potently inhibits mycelial growth of Phytophthora capsici, with an EC50 value of 6.78 × 10-4 μg/mL^[1]. Oxathiapiprolin (0-48 h) potently inhibits sporangium production by Phytophthora capsici, with an EC50 of 1.29 × 10-5 μg/mL^[1]. Oxathiapiprolin (0-10 μg/mL; 1 h) inhibits zoospore release in Phytophthora capsici, with an EC50 value of 4.38 μg/mL^[1]. Oxathiapiprolin (1-10 μg/mL; 10 min) inhibits the motility of Phytophthora capsici zoospores at concentrations of 1 μg/mL and above^[1]. Oxathiapiprolin (0-8 days) potently inhibits mycelial development of Pseudoperonospora cubensis, with an EC50 value of 3.10 × 10-4 μg/mL^[1]. Oxathiapiprolin inhibits zoospore release of Pseudoperonospora cubensis, with an EC50 value of 0.13 μg/mL^[1].

References:
[1]. Miao J, et al. Activity of the novel fungicide oxathiapiprolin against plant-pathogenic oomycetes. Pest Manag Sci. 2016;72(8):1572-1577.