(R)-Octopamine |
Katalog-Nr.GC79263
One-Click Copy Product Info
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(R)-Octopamine is a Gs-coupled receptor agonist.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 876-04-0
Sample solution is provided at 25 µL, 10mM.
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In Vitro, (R)-Octopamine (0.1 nM-10 μM; 20 min after IBMX preincubation) potently activates wild-type BmOAR2 in HEK-293 cells to elevate intracellular cAMP levels, with an EC50 of approximately 1.0 nM and maximum response at 10 nM[1]. (R)-Octopamine interacts with BmOAR2 via hydrogen bonds between its phenolic OH group and Ser202/Tyr300, and between its NH2/β-OH groups and Asp115[1].
References:
[1]. Xi Chen, et al. Amino acid residues involved in the interaction with the intrinsic agonist (R)-octopamine in the.BETA.-adrenergic-like octopamine receptor from the silkworm Bombyx mori. Journal of Pesticide Science 36(4):473-480.
| Cas No. | 876-04-0 | SDF | |
| Formula | C8H11NO2 | M.Wt | 153.18 |
| Löslichkeit | Storage | Store at -20°C | |
| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 6.5283 mL | 32.6413 mL | 65.2827 mL |
| 5 mM | 1.3057 mL | 6.5283 mL | 13.0565 mL |
| 10 mM | 652.8 μL | 3.2641 mL | 6.5283 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >95.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)