GLPBio

Diabetes

Products Related to Diabetes(256)

  • GC43762 structure
    GC43762GLP-1 (7-36) amide (trifluoroacetate salt)
    Purity: >98.00%

    GLP-1 (7-36) amide is a peptide hormone released from intestinal L-cells upon nutrient consumption.

  • GC43763 structure
    GC43763GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat) (trifluoroacetate salt)
    Purity: >95.00%

    Glucagon-like peptide-1 (GLP-1) (7-37) is an endogenous incretin hormone and truncated form of GLP-1 (1-37) that is produced via cleavage of preproglucagon in the pancreas and intestine.

  • GC43764 structure
    GC43764GLP-2 (human) (trifluoroacetate salt)
    Purity: >95.00%

    Glucagon-like peptide-2 (GLP-2) is an endogenous peptide hormone formed in L cells of the small and large intestine by cleavage of proglucagon in response to nutrient ingestion.

  • GC43766 structure
    GC43766Glucagon Receptor Antagonist Inactive Control
    CAS: 362482-00-6
    Purity: >95.00%

    An inactive control for glucagon receptor antagonist I

  • GC43768 structure
    GC43768Glucocerebrosides (Gaucher's spleen)
    CAS: 85305-87-9
    Purity: >98.00%

    Glucocerebrosides are formed by the tethering of glucose to a ceramide by glucosylceramide synthase.

  • GC43773 structure
    GC43773Glyburide (potassium salt)
    CAS: 52169-36-5
    Purity: >98.00%

    Glyburide is a sulfonylurea and an inhibitor of sulfonylurea receptor 1 (SUR1) linked to ATP-sensitive potassium channel Kir6.2 (IC50 = 4.3 nM).

  • GC43800 structure
    GC43800GW 9578
    CAS: 247923-29-1
    Purity: >98.00%

    GW9578 ist ein Subtyp-selektiver PPARα-Agonist (EC50s von 5 und 50 nM fÜr murines und humanes PPAR-α) mit starker lipidsenkender AktivitÄt.

  • GC43803 structure
    GC43803HA-1077 (hydrochloride)
    CAS: 203911-27-7
    Purity: >98.00%

    Fasudil (HA-1077; AT877) dihydrochloride is a nonspecific RhoA/ROCK inhibitor and also has inhibitory effect on protein kinases, with an Ki of 0.33 μM for ROCK1, IC50s of 0.158 μM and 4.58 μM, 12.30 μ ;M, 1.650 μM fÜr ROCK2 bzw. PKA, PKC, PKG. HA-1077 (Hydrochlorid) ist auch ein potenter Ca2+-Kanalantagonist und Vasodilatator.

  • GC44024 structure
    GC44024Lactisole
    CAS: 150436-68-3
    Purity: >98.00%

    Lactisole is a canonical antagonist of sweet taste receptor, selectively targeting to T1R3 subunit.

  • GC44077 structure
    GC44077Lithocholic Acid 3-sulfate (sodium salt)
    CAS: 64936-81-8
    Purity: >98.00%

    Lithocholic acid 3-sulfate is a metabolite of the secondary bile acid lithocholic acid.

  • GC44191 structure
    GC44191MHY908
    CAS: 1393371-39-5
    Purity: >98.00%

    MHY908 ist ein potenter dualer Agonist von PPARα und PPARγ.

  • GC44226 structure
    GC44226MLS-0322825 Cmpd 23
    CAS: 1908414-82-3
    Purity: >98.00%

    MLS-0322825 Cmpd 23 ist ein selektiver Inhibitor der niedermolekularen Proteintyrosinphosphatase (LMPTP) mit einem IC50-Wert von 0,8 μM LMPTP-A.

  • GC44300 structure
    GC44300N-Acetylagmatine (acetate salt)
    Purity: >95.00%

    Agmatine is a natural polyamine formed by the enzymatic decarboxylation of arginine.

  • GC44341 structure
    GC44341ND-336
    CAS: 1807453-83-3
    Purity: >95.00%

    ND-336 ist ein selektiver Inhibitor der Matrix-Metalloproteinase (MMP)-2, MMP-9 und MMP-14 mit Kis-Werten von 85, 150 bzw. 120 nM.

  • GC44441 structure
    GC44441N-Oleoyl Leucine
    CAS: 136560-76-4
    Purity: >98.00%

    N-Oleoyl Leucine is a fatty acid–amino acid conjugate (FAAA) that belongs to the family of N-acyl amino acids.

  • GC44484 structure
    GC44484Obestatin (rat) (trifluoroacetate salt)
    Purity: >95.00%

    Obestatin is a 23-amino acid peptide hormone that is formed by cleavage of the ghrelin and obestatin prepropeptide.

  • GC44518 structure
    GC44518Osteocalcin (1-49) (human) (trifluoroacetate salt)
    CAS: 136461-80-8
    Purity: >95.00%

    Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone.

  • GC44524 structure
    GC44524Oxyntomodulin (bovine, porcine) (trifluoroacetate salt)
    Purity: >95.00%

    Oxyntomodulin, also known as glucagon-37, is a 37-amino acid peptide produced in bovine and porcine gut.

  • GC44544 structure
    GC44544Palmitoleic Acid (sodium salt)
    CAS: 6610-24-8
    Purity: >95.00%

    Palmitoleic acid is an ω-7 monounsaturated fatty acid that is a common constituent of the triglycerides of human adipose tissue.

  • GC44645 structure
    GC44645Pioglitazone (potassium salt)
    CAS: 1266523-09-4
    Purity: >98.00%

    Pioglitazon (U 72107) Kalium ist ein oral aktives und selektives PPARγ (Peroxisom-Proliferator-aktivierter Rezeptor)-Agonist mit hoher AffinitÄtsbindung an PPARγ LigandenbindungsdomÄne mit EC50 von 0,93 μM und 0,99 μM fÜr menschliches bzw. Maus-PPARγ.

  • GC44660 structure
    GC44660Platensimycin
    CAS: 835876-32-9
    Purity: >95.00%

    Platensimycin (PTM) is an antibiotic produced by S.

  • GC44775 structure
    GC44775PTP1B Inhibitor
    CAS: 765317-72-4
    Purity: >98.00%

    PTP1B Inhibitor ist ein nicht-kompetitiver allosterischer Inhibitor der Proteintyrosinphosphatase PTP1B mit einem IC50 von 8 μM.

  • GC44811 structure
    GC44811Remogliflozin etabonate
    CAS: 442201-24-3
    Purity: >99.00%

    Remogliflozinetabonat (GSK189075) ist ein oral aktiver, selektiver und niedrigaffiner Natriumglucose-Cotransporter (SGLT2)-Inhibitor mit Ki-Werten von 1,95 μM, 2,14 μM, 43,1 μM, 8,57 μM fÜr hSGLT2, rSGLT2, hSGLT1 bzw. rSGLT1.

  • GC44851 structure
    GC44851Rosiglitazone (potassium salt)
    CAS: 316371-84-3
    Purity: >98.00%

    Rosiglitazon (BRL 49653)-Kalium ist ein oral aktives selektives PPARγ Agonist (EC50: 60 nM, Kd: 40 nM).