Ubiquitination/ Proteasome

Quercetin ist ein wichtiger diätetischer Flavonoid, der in Gemüse, Obst, Samen, Nüssen, Tee und Rotwein vorkommt.

Icariin ist ein Flavonolglykosid.

Silibinin is an orally active flavonoid with hepatoprotective and anticancer effects.

Vinorelbine is an anti-mitotic drug, a semi-synthetic derivative of paclitaxel, that exerts its antitumor effect by inhibiting microtubule polymerization in tumor cells. Vinorelbine is primarily used to treat malignant tumors such as non-small cell lung cancer and metastatic breast cancer.

Magnolol is a lignan compound extracted from the bark of Magnolia officinalis with multiple pharmacological activities. Magnolol is a dual agonist of RXRα (EC 50 =10.4µM) and PPARγ (EC 50 =17.7µM).

Taxifolin is a tyrosinase inhibitor and has significant collagenase inhibitory activity, with an IC 50 value of 193.3μM.

Nobiletin is a polymethoxylated flavone extracted from citrus plants. Nobiletin has a variety of pharmacological effects, including antioxidant, anti-inflammatory, and anti-tumor properties.

Polydatin is a natural stilbene glucoside extracted from the traditional Chinese medicine Polygonum cuspidatum , and Polydatin is the glycoside form of resveratrol.

Salvianolic acid B is a water-soluble phenolic compound extracted from Salvia miltiorrhiza, which has many pharmacological effects, including anti-tumor, anti-inflammation and anti-oxidation. Salvianolic acid B can cross the blood-brain barrier and directly act on the central nervous system.

Parthenolide ist ein NF-κB-Inhibitor mit IC 50 -Werten für Eca109-, KYSE-510-, SiHa- und MCF-7-Zellen von ungefähr 10.3, 13.3, 8.42 und 9.54μM nach 48 Stunden.

Luteolin is a flavonoid compound with multiple functions such as anti-inflammatory, antioxidant, and anti-cancer. Luteolin is an effective inhibitor of nuclear factor erythroid 2-related factor 2 (Nrf2).

Ein Triterpenoid mit vielfältigen biologischen Aktivitäten.