Specialized Pro-Resolving Mediators

Eine Trihydroxy-Fettsäure mit einem konjugierten Tetraen.

Lipoxin A4 methyl ester (LXA4 methyl ester) is a more lipid soluble, prodrug formulation of the transcellular metabolite LXA4.

Lipoxin B4 (LXB4) is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15(S)-HpETE by human leukocytes.

Docosahexaenoic acid-d5 (DHA-d5) is intended for use as an internal standard for the quantification of DHA (Item No. 90310) by GC- or LC-MS.

Lipoxin A5 (LXA5) is produced by enzymatic transformation of EPA by leukocytes.

10(S),17(S)-DiHDHA (auch als Neuroprotectin D1 bekannt, wenn es in neuronalen Geweben produziert wird) ist eine von DHA abgeleitete DihydroxyfettsÄure, die starke schÜtzende und entzÜndungshemmende AktivitÄten aufweist.

17(S)-HpDHA is a mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, human glial cells, and mouse brain.

7-epi Maresin 1 is the inactive 7(S) epimer of Maresin 1, which contains a 7(R) hydroxyl group.

Maresin 2 ist ein entzÜndungshemmender und auflÖsungsfÖrdernder Mediator aus menschlichen Makrophagen.

Protectin D1, Neuroprotectin D1, wenn es von neuralen Zellen erzeugt wird, ist ein Mitglied einer neuen Familie bioaktiver Produkte, die aus DocosahexaensÄure erzeugt werden.

Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.

Lipoxin B4 (LXB4) methyl ester is a lipid soluble prodrug form of the transcellular metabolite LXB4.

14(S)-HDHA (14(S)-HDoHE) ist ein Oxygenierungsprodukt der DocosahexaensÄure (DHA).

Resolvins are a group of polyhydroxylated metabolites of docosahexaenoic acid (DHA) found in the inflammatory exudates of aspirin-treated experimental animals.

17(S)-HDHA is a primary mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, and mouse brain.

17(R)-Resolvin D1 (17(R)-RvD1) is an aspirin-triggered epimer of RvD1 that reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, with equipotency to RvD1 (EC50 = ~30 nM).

Resolvin D1-Methylester (RvD1-Methylester) ist der Methylester von Resolvin D1.

Resolvin D2 (RvD2) is a lipid mediator biosynthesized by the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase.

Resolvin D3 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties.

Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and function.

The lipoxins are trihydroxy fatty acids containing a 7,9,11,13-conjugated tetraene.

Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.

17(R)-Resolvin D4 (17(R)-RvD4) is an aspirin-triggered epimer of RvD4 .

Maresin conjugates in tissue regeneration 1 (MCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid in macrophages at the site of inflammation.