Resolvin D1 methyl ester (Synonyms: 17(S)-Resolvin D1 methyl ester, RvD1 methyl ester) |
| Katalog-Nr.GC41230 |
Resolvin D1-Methylester (RvD1-Methylester) ist der Methylester von Resolvin D1.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 937738-63-1
Sample solution is provided at 25 µL, 10mM.
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Resolvin D1 is produced physiologically from the sequential oxygenation of docosahexaenoic acid by 15- and 5-lipoxygenase . It reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, with an EC50 value of ~30 nM. RvD1 methyl ester is a methyl ester version of the free acid that may act as a lipophilic prodrug form that will alter its distribution and pharmacokinetic properties. The methyl ester moiety is susceptible to cleavage by intracellular esterases, leaving the free acid.
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