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TH-Z93

Katalog-Nr.GC71120 Copy One-Click Copy Product Info

TH-Z93, ein lipophiles Bisphosphonat, ist ein FPPS-Hemmer (IC50: 90 nM).

Products are for research use only. Not for human use. We do not sell to patients.

TH-Z93 Chemische Struktur

Cas No.: 2260887-09-8

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1 mg
135,00 $
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5 mg
342,00 $
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10 mg
495,00 $
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25 mg
765,00 $
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Sample solution is provided at 25 µL, 10mM.



Description of TH-Z93

TH-Z93, a lipophilic bisphosphonate, is a FPPS inhibitor (IC50: 90 nM).

TH-Z93 (20 μg, i.p.) exhibits strong prophylactic effects in a pathogenic influenza model[1].

Chemical Properties of TH-Z93

Cas No. 2260887-09-8 SDF
Formula C12H22N2O7P2 M.Wt 368.26
Löslichkeit H2O : 1.89 mg/mL (5.13 mM; ultrasonic and warming and adjust pH to 10 with NaOH and heat to 60°C) Storage -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of TH-Z93

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.7155 mL 13.5774 mL 27.1547 mL
5 mM 543.1 μL 2.7155 mL 5.4309 mL
10 mM 271.5 μL 1.3577 mL 2.7155 mL
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In vivo Formulation Calculator (Clear solution) of TH-Z93

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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