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| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 10mM (in 1mL DMSO) | $441.00 | In Stock | 1 | |
| 5 mg | $405.00 | In Stock | 1 | |
| 10 mg | $720.00 | In Stock | 1 | |
| 25 mg | $1,485.00 | In Stock | 1 | |
| 50 mg | $2,295.00 | In Stock | 1 | |
| 100 mg | $3,420.00 | In Stock | 1 |
TMP780 is an inverse agonist of RORγt with an IC50 of 13 nM. RORγt is a tractable drug target for the treatment of cutaneous inflammatory disorders[1].
[1]. Skepner J, et al. Pharmacologic inhibition of RORγt regulates Th17 signature gene expression and suppresses cutaneous inflammation in vivo. J Immunol. 2014 Mar 15;192(6):2564-75.