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DNA-GAGA

Catalog No.GC81656 Copy One-Click Copy Product Info

DNA-GAGA is a slow substrate for Ricin toxin A-chain (RTA).

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DNA-GAGA Chemical Structure

Cas No.: 110138-50-6

Size Price Stock Qty
100nmol
$216.00
In stock

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Sample solution is provided at 25 µL, 10mM.



Description of DNA-GAGA

DNA-GAGA is a slow substrate for Ricin toxin A-chain (RTA). RTA depurinates a single adenylate on a GAGA stem-loop region of eukaryotic 28S RNA, making it a potent toxin [1].

References:
[1]. Tim K Amukele, et al. Ricin A-chain activity on stem-loop and unstructured DNA substrates. Biochemistry. 2005 Mar 22;44(11):4416-25.

Chemical Properties of DNA-GAGA

Cas No. 110138-50-6 SDF
Formula C40H49N20O20P3 M.Wt 1222.86
Solubility Storage Store at -20°C, away from moisture
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of DNA-GAGA

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1 mg 5 mg 10 mg
1 mM 817.8 μL 4.0888 mL 8.1776 mL
5 mM 163.6 μL 817.8 μL 1.6355 mL
10 mM 81.8 μL 408.9 μL 817.8 μL
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In vivo Formulation Calculator (Clear solution) of DNA-GAGA

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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