Nucleoside Antimetabolite/Analogue
Nucleoside analouges belong to the fmalily of antimetablits that resemble the neleosieds for uptake and metaolism that inibitr dna sytnse and couase cain termination. It is a durg target for cacner and viral infcations.
Products for Nucleoside Antimetabolite/Analogue
- Cat.No. Product Name Information
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GC69793
(R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose
(R)-5-O-Benzoyl-1,2-di-O-isopropylidene-alpha-D-xylofuranose is a purine nucleoside analogue. Purine nucleoside analogues have broad anti-tumor activity and target inert lymphoid malignancies. The anticancer mechanism in this process depends on inhibiting DNA synthesis, inducing apoptosis (cell death), etc.
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GC68484
1,2-O-Isopropylidene-5-O-p-toluoyl-a-D-xylofuranose
1,2-O-Isopropylidene-5-O-p-toluoyl-a-D-xylofuranose is a purine nucleoside analogue. Purine nucleoside analogues have broad anti-tumor activity and target malignant tumors in the inert lymphatic system. The anticancer mechanism in this process depends on inhibiting DNA synthesis, inducing apoptosis (cell death), etc.
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GC65551
1-(2'-O-4-C-Methylene-beta-D-ribofuranosyl)thymine
1-(2'-O-4-C-Methylene-beta-D-ribofuranosyl)thymine is a bicyclic nucleoside.
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GC71294
1-(2-Deoxy-β-D-threo-pentofuranosyl)thymine
1-(2-Deoxy-β-D-threo-pentofuranosyl)thymine is a thymidine analog.
-
GC65038
1-Methylinosine
1-methyl Inosine, N1-Methylinosine
1-Methylinosine is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA. -
GC73523
2'-Deoxy-N3-methylcytidine hydriodide
2’-Deoxy-N3-metlcytidine driodide is a purine nucleoside analog.
-
GC65489
2'-F-Bz-dC Phosphoramidite
2'-F-Bz-dC Phosphoramidite can be used in the synthesis of oligoribonucleotides.
-
GC66651
2'-O,4'-C-Methyleneadenosine
LNA-A
2'-O,4'-C-Methyleneadenosine (LNA-A) is a locked nucleic acid (LNA) and is also an adenosine analog. -
GC66654
2'-O,4'-C-Methylenecytidine
LNA-C(Bz)
2'-O,4'-C-Methylenecytidine (LNA-C(Bz)) is a bicyclic nucleoside analogue with fixed N-type conformation. 2'-O,4'-C-Methylenecytidine can be used to synthesize oligonucleotides. 2'-O,4'-C-Methylenecytidine forms duplexes with complementary DNA and RNA strands. -
GC66655
2'-O,4'-C-Methyleneguanosine
LNA-G
2′-O,4′-C-Methyleneguanosine (LNA-G) is a reverse guanine analogue, where LNA (locked nucleic acid) is a nucleic acid analogue. LNA modification can be used in a variety of applications such as effective binding affinity to complementary sequences and greater nuclease resistance than natural nucleotides, offering great potential for applications in disease diagnosis and research. LNA-G is also available via KOD DNA polymerase, which allows the integration of LNA-G nucleotides into the DNA strand. -
GC65170
2′,3′-Di-O-acetylguanosine
2′,3′-Di-O-acetylguanosine is a nucleoside analog.
-
GC67384
2′-Deoxy-β-L-uridine
2'-Deoxy-β-L-uridine is a nucledside analogue and a specific substrate for the viral enzyme, shows no stereospecificity against herpes simplex 1 (HSV1) thymidine kinase (TK). 2′-Deoxy-β-L-uridine exerts antiviral activity via the interation of 5'-triphosphates with the viral DNA polymerase.
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GC61667
2′-Deoxy-2′-fluoroadenosine
2′-Deoxy-2′-fluoroadenosine can be used for thesynthesisof 2′-Deoxy-2′-fluoro-modified oligonucleotides hybridized with RNA. 2′-Deoxy-2′-fluoroadenosine can be cleaved efficiently by E. coli purine nucleoside phosphorylase (PNP) to the toxic agent 2-fluoroadenine (FAde). 2′-Deoxy-2′-fluoroadenosine shows excellent in vivo activity against tumors expressing E. coli PNP.
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GC62530
2’-O-Me-C(Bz) Phosphoramidite
2’-O-Me-C(Bz) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.
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GC62529
2’-OMe-A(Bz) Phosphoramidite
2’-OMe-A(Bz) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.
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GC62531
2’-OMe-G(ibu) Phosphoramidite
2’-OMe-G(ibu) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.
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GC48440
2'-Deoxycytidine-5'-triphosphate (sodium salt)
dCTP
2'-Deoxycytidine-5'-triphosphate (sodium salt) (dCTP trisodium salt) is a nucleoside triphosphate that can be used for DNA synthesis. -
GC33430
2'-Deoxypseudoisocytidine
2'-Deoxypseudoisocytidine is a nucleoside analogue.
-
GC35072
2'-O,4'-C-Methyleneuridine
2'-O,4'-C-Methyleneuridine (Compound 15a) is a bicyclic nucleoside.
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GC64983
2-Amino-2'-deoxyadenosine
2-Amino-2'-deoxyadenosine is a deoxyribonucleoside used for the oligonucleotide synthesis.
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GC71208
2-Methyladenosine
2-Methyladenosine is an adenosine analogue.
-
GC73004
2-Methylthioadenosine
2-Metlthioadenosine is a purine nucleoside analog.
-
GC65083
3'-Azido-3'-deoxy-5-fluorocytidine
3'-Azido-3'-deoxy-5-fluorocytidine (Compound 12) is a cytidine derivative.
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GC73400
3'-Azido-3'-deoxyuridine
3’-Azido-3’-deoxyuridine is a purine nucleoside analogue.
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GC71204
3'-O-(2-Methoxyethyl)guanosine
3’-O-(2-Methoxyethyl)guanosine is a guanosine analogue.
-
GC64985
3'-O-Methylguanosine
3'-O-Methylguanosine is a methylated nucleoside analogs and a RNA chain terminator.
-
GC35105
3'-Azido-3'-deoxy-beta-L-uridine
3'-Azido-3'-deoxy-beta-L-uridine (Compound 25) is a nucleoside derivative.
-
GC60023
3'-Deoxyuridine-5'-triphosphate
3'-dUTP
3'-Deoxyuridine-5'-triphosphate (3'-dUTP) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. -
GC61862
3'-Deoxyuridine-5'-triphosphate trisodium
3'-dUTP trisodium
3'-Deoxyuridine-5'-triphosphate trisodium (3'-dUTP trisodium) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II. -
GC65084
3-Methylcytidine
3-Methylcytidine, a urinary nucleoside, can be used as a biomarker of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.
-
GC68557
4-Thio-2'-deoxyuridine
2′-Deoxy-4-thiouridine; 4-Thiodeoxyuridine
4-Thio-2'-deoxyuridine is a purine nucleoside analogue. Purine nucleoside analogues have broad anti-tumor activity, targeting inert lymphatic system malignancies. The anticancer mechanism in this process depends on inhibiting DNA synthesis and inducing cell apoptosis.
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GC42474
4-Thiouridine
NSC 518132, 4-SU
4-Thiouridine(4sU) is a ribonucleoside analogue that can be used for RNA analysis and (m)RNA labeling. -
GC73521
5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite
N1-Methylpseudouridine CEP
5'-DMT-2'-O-TBDMS-N1-Metl-PseudoUridine-CE-Phosphoramidite is a purine nucleoside analog. -
GC65520
5'-DMT-3'-TBDMS-ibu-rG
5'-DMT-3'-TBDMS-ibu-rG is is a modified nucleoside.
-
GC65402
5'-O-DMT-2'-O-TBDMS-Bz-rC
5'-O-DMT-2'-O-TBDMS-Bz-rC is a modified nucleoside and can be used to synthesize DNA or RNA.
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GC65164
5'-O-DMT-2'-O-TBDMS-rI
5'-O-DMT-2'-O-TBDMS-rI is a modified nucleoside.
-
GC65396
5'-O-DMT-ibu-dC
5'-O-DMT-ibu-dC can be used in the synthesis of oligodeoxyribonucleotides.
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GC64982
5'-O-DMT-N2-DMF-dG
5'-O-DMT-2'-O-TBDMS-rI is a modified nucleoside.
-
GC65482
5'-O-DMT-N6-ibu-dA
5'-O-DMT-N6-ibu-dA can be used in the synthesis of oligodeoxyribonucleotides.
-
GC65562
5'-O-DMT-N6-Me-2'-dA
5'-O-DMT-N6-Me-2'-dA is a nucleoside with protective and modification effects.
-
GC65401
5'-O-TBDMS-dU
5'-O-TBDMS-dU can be used in the synthesis of oligoribonucleotides.
-
GC71033
5'-ODMT cEt G Phosphoramidite (Amidite)
5'-ODMT cEt G Phosphoramidite Amidite is a potent nucleic acid analog.
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GC71035
5'-ODMT cEt m5U Phosphoramidite (Amidite)
5'-ODMT cEt m5U Phosphoramidite Amidite is a locked nucleic acid (LNA) analog.
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GC73179
5'-ODMT cEt N-Bz A Phosphoramidite (Amidite)
5'-ODMT cEt N-Bz A Phosphoramidite Amidite is a locked nucleic acid (LNA) analogue.
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GC71034
5'-ODMT cEt N-Bzm5 C Phosphoramidite (Amidite)
5'-ODMT cEt N-Bzm5 C Phosphoramidite Amidite is a potent nucleic acid analog.
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GC62157
5’-O-DMT-2’-O-TBDMS-Ac-rC
5’-O-DMT-2’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.
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GC62149
5’-O-DMT-2’-TBDMS-Uridine
5’-O-DMT-2’-TBDMS-Uridine is a deoxyribonucleoside used for the oligonucleotide synthesis.
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GC62532
5’-O-DMT-3’-O-TBDMS-Ac-rC
5’-O-DMT-3’-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.
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GC62573
5’-O-DMT-Bz-rC
5'-O-DMT-Bz-Rc is a modified nucleoside and can be used to synthesize DNA or RNA.
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GC62574
5’-O-DMT-N4-Ac-2’-F-dC
5’-O-DMT-N4-Ac-2’-F-dC is a modified nucleoside and can be used to synthesize DNA or RNA.
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GC62575
5’-O-DMT-N4-Bz-2’-F-dC
5’-O-DMT-N4-Bz-2’-F-dC is a nucleoside with protective and modification effects.
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GC62576
5’-O-DMT-N4-Bz-5-Me-dC
5’-O-DMT-N4-Bz-5-Me-dC is a modified nucleoside.
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GC62578
5’-O-TBDMS-Bz-dA
5’-O-TBDMS-Bz-dA is a nucleoside with protective and modification effects.
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GC62579
5’-O-TBDMS-dA
5’-O-TBDMS-dA is a modified nucleoside and can be used to synthesize DNA or RNA.
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GC62580
5’-O-TBDMS-dG
5’-O-TBDMS-dG is a modified nucleoside.
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GC62581
5’-O-TBDMS-dT
5’-O-TBDMS-dT is a nucleoside with protective and modification effects.
-
GC61432
5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine
5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine?is an adenosine derivative and can be used as an intermediate for oligonucleotides synthesis.
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GC64952
5-Aza-7-deazaguanine
5-Aza-7-deazaguanine is a substrate for wild-type (WT) E. coli purine nucleoside phosphorylase and its Ser90Ala mutant in the synthesis of base-modified nucleosides.
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GC10946
5-Azacytidine
Antibiotic U 18496, 5AzaC, Ladakamycin, Mylosar, NSC 102816, NSC 103627, U 18496, WR 183027
5-Azacytidine (also known as 5-AzaC), a compound belonging to a class of cytosine analogues, is a DNA methyl transferase (DNMT) inhibitor that exerts potent cytotoxicity against multiple myeloma (MM) cells, including MM.1S, MM.1R, RPMI-8266, RPMI-LR5, RPMI-Dox40 and Patient-derived MM, with the half maximal inhibition concentration IC50 values of 1.5 μmol/L, 0.7 μmol/L, 1.1 μmol/L, 2.5 μmol/L, 3.2 μmol/L and 1.5 μmol/L respectively. -
GC73520
5-Azidomethyl-2'-deoxyuridine
5-AmdU; α-Azidothymidine
5-Azidometl-2'-deoxyuridine (5-AmdU) is a purine nucleoside analog. -
GC11940
5-BrdU
BrdU, Bromodeoxyuridine, Broxuridine, NSC 38297
5-BrdU (5-bromo-2-deoxundine5-BrdU) is a synthetic thymidine bromide analog that is commonly used to measure DNA synthesis and label dividing cells. -
GC71207
5-Ethyluridine
5-Ethyluridine is a purine nucleoside analogue.
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GC62547
5-O-TBDMS-N4-Benzoyl-2-deoxycytidine
5-O-TBDMS-N4-Benzoyl-2-deoxycytidine is a modified nucleoside.
-
GC30548
6-Amino-5-nitropyridin-2-one
6-Amino-5-nitropyridin-2-one is a pyridine base and used as a nucleobase of hachimoji DNA, in which it pairs with 5-aza-7-deazaguanine.
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GC60031
6-Azathymine
6-Azathymine, a 6-nitrogen analog of thymine, is a potent D-3-aminoisobutyrate-pyruvate aminotransferase inhibitor.
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GC32975
6-Mercaptopurine hydrate
6-MP
An inhibitor of purine synthesis and interconversion -
GC65082
6-O-Methyl Guanosine
6-O-Methyl Guanosine is a modified nucleoside.
-
GC35171
6-Thioinosine
6-Thioinosine (6TI) is a purine antimetabolite, acts as an anti-adipogenesis agent, downregulates mRNA levels of PPAR γ and C/EBPα, as well as PPAR γ target protein such as LPL, CD36, aP2, and LXRα.
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GC66060
7-Iodo-2',3'-dideoxy-7-deaza-guanosine
7-Iodo-2',3'-dideoxy-7-deaza-guanosine is a dideoxynucleoside that can be used in DNA synthesis and sequencing reactions.
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GC71545
7-Methyl-guanosine-5'-triphosphate sodium
7-Methyl-guanosine-5'-triphosphate (m7GTP) sodium is a guanosine 5'-phosphate.
-
GC30531
7-Methylguanosine
m7G, 7-MeGua
A nucleotide analog -
GC65525
7-TFA-ap-7-Deaza-dG
5'-O-TBDMS-dG is a modified nucleoside.
-
GC73399
9-(β-D-Xylofuranosyl)adenine
9-(β-D-Xylofuranosyl)adenine is an adenosine analog.
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GC13805
Abacavir
-
GC13432
Adenine
High affinity adenine receptor agonist
-
GC14106
Adenosine
NSC 7652
nucleoside -
GC65462
Adenosine 5′-monophosphoramidate sodium
Adenosine 5′-monophosphoramidate sodium is an adenosine derivative and can be used as an intermediate for nucleotide synthesis.
-
GC68625
Adenosine-d2
Adenine riboside-d2; D-Adenosine-d2
Adenosine-d2 is the deuterated form of adenosine. Adenosine (adenine riboside) is a commonly occurring endogenous secretion that acts through four G protein-coupled receptors (A1, A2A, A2B, and A3). Adenosine affects almost all aspects of cellular physiology, including neuronal activity, vascular function, platelet aggregation, and blood cell regulation.
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GC73524
Alpha-Adenosine
Alpha-Adenosine is a purine nucleoside analog.
-
GC73525
Alpha-Guanosine
Alpha-Guanosine is a purine nucleoside analog.
-
GC72841
Arabinosylhypoxanthine
Arabinosylpoxanthine is a purine nucleoside analog.
-
GC11843
Azaguanine-8
8-AG
Azaguanine-8 is a purine analogue that shows antineoplastic activity. Azaguanine-8 functions as an antimetabolite and easily incorporates into ribonucleic acids, interfering with normal biosynthetic pathways, thus inhibiting cellular growth. -
GC15866
Capecitabine
Ro 091978
DNA, RNA and protein synthesis inhibitor -
GC12748
Carmofur
HCFU
Cytostatic derivative of fluorouracilm,antineoplatic agent -
GC64261
Censavudine
OBP-601; BMS-986001
Censavudine (OBP-601; BMS-986001), a nucleoside analog, is a nucleoside reverse transcriptase inhibitor. -
GC35693
CI 972 (anhydrous)
CI 972 (anhydrous) is a potent, orally active, and competitive inhibitor of purine nucleoside phosphorylase (PNP) (Ki=0.83 μM) under development as a T cell-selective immunosuppressive agent.
-
GC15219
Clofarabine
Clolar, Evoltra
Antimetabolite,inhibit DNA polymerase and ribonucleotide reductase -
GC33177
CNDAC
CNDAC is a major metabolite of oral drug sapacitabine, and a nucleoside analog.
-
GC38382
CNDAC hydrochloride
CNDAC hydrochloride is a metabolite of the orally active agent sapacitabine, and a nucleoside analog.
-
GC13070
Cytarabine
1βDArabinofuranosylcytosine, NSC 63878, NSC 287459, U19920A
Cytarabine (Ara-C) is a cytosine analog that primarily inhibits the function of DNA polymerase to block DNA synthesis. -
GC14961
Cytarabine hydrochloride
DNA synthsis inhibitor
-
GC13729
Cytidine
β-D-Cytidine, NSC 20258
pyrimidine nucleoside -
GC14485
Dacarbazine
NCI C04717, NSC 45388
Antineoplastic( malignant melanoma and sarcomas) -
GC34123
Deoxycytidine triphosphate (dCTP)
Deoxycytidine triphosphate (dCTP) (dCTP) is a nucleoside triphosphate that can be used for DNA synthesis.
-
GC33494
Deoxypseudouridine
Deoxypseudouridine is a nucleoside analog.
-
GC73068
Deoxythymidine-5'-triphosphate-13C10 dilithium
dTTP-13C10 dilithium
Deoxytmidine-5'-triphosphate-13C10 (dTTP-13C10) dilithium is 13C-labeled Deoxytmidine-5'-triphosphate. -
GC62150
DMT-dC(ac) Phosphoramidite
DMT-dC(ac) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.
-
GC62538
DMT-dG(dmf) Phosphoramidite
DMT-dG(dmf) Phosphoramidite is a phosphinamide monomer that can be used in the preparation of oligonucleotides
-
GC71465
DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite
DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite (compound 1B) is a phosphoramidite of 5-Fluoro-2'-deoxycytidine.
-
GC66711
DMTr-LNA-5MeU-3-CED-phosphoramidite
DMTr-LNA-5MeU-3-CED-phosphoramidite is a nucleoside derivative.