GLPBio

FF-MAS

Catalog No.: GC18815Purity:≥90.00%Synonyms: Follicular Fluid Meiosis-activating Sterol

Follicular fluid meiosis-activating sterol (FF-MAS) is an intermediate in cholesterol biosynthesis from lanosterol that is found at high concentrations in mammalian ovarian follicular fluid.

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FF-MAS
Cas No.: 64284-64-6
1mgIn Stock
$1,810.00
1

Citations

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  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

Follicular fluid meiosis-activating sterol (FF-MAS) is an intermediate in cholesterol biosynthesis from lanosterol that is found at high concentrations in mammalian ovarian follicular fluid. It increases survival of human oocytes isolated from patients with polycystic ovarian syndrome (PCOS) and improves cytoplasmic maturation of immature rodent and porcine oocytes in vitro. FF-MAS promotes completion of meiotic maturation to metaphase II and increases the rate of successful in vitro fertilization (IVF) in isolated mouse oocytes. Formulations containing FF-MAS have been used to improve embryo quality and implantation rate during IVF.

Product Documents

Purity:≥90.00%Appearance:A solid

Chemical Properties

CAS No.
64284-64-6
Synonyms
Follicular Fluid Meiosis-activating Sterol
Chemical Name
(3β,5α)-4,4-dimethyl-cholesta-8,14,24-trien-3-ol
SMILES
CC1(C)[C@@H](O)CC[C@@]2(C)[C@@]1([H])CCC3=C2CC[C@@]4(C)C3=CC[C@]4([H])[C@@H](CC/C=C(C)/C)C
Molecular Formula
C29H46O
Molecular Weight
410.7
Solubility
Chloroform: Slightly Soluble
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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