Amenamevir -d 6 (ASP2151-d 6 ) is the deuterium labeled Amenamevir. Amenamevir is a helicase-primase inhibitor which has potent antiviral activity against HSVs with an EC 50 of 14 ng/mL.
In Vitro, Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
In Vitro, Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.