Cy3 hydrazide is a carbonyl-reactive dye, an analog of Cy3® hydrazide.
Cyanine3 dyes have been used to label biological molecules for fluorescence imaging and other fluorescence-based biochemical analysis. They are widely used for labeling peptides, proteins and oligos etc.
Cy3 hydrazide can be used to label various carbonyl-containing molecules such as antibodies and other glycoproteins after periodate oxidation, proteins which have undergone deamination or oxidative stress, or reducing saccarides. Cyanine3 is compatible with a number of fluorescent instruments.
References:
[1]. Pan D, Qin H, Cooperman BS. Synthesis and functional activity of tRNAs labeled with fluorescent hydrazides in the D-loop. RNA. 2009 Feb;15(2):346-54.
[2]. Tamarit J, de Hoogh A, Obis E, et al. Analysis of oxidative stress-induced protein carbonylation using fluorescent hydrazides. J Proteomics. 2012 Jun 27;75(12):3778-88.
[3]. Kameyama A, Kaneda Y, Yamanaka H, et al. Detection of oligosaccharides labeled with cyanine dyes using matrix-assisted laser desorption/ionization mass spectrometry. Anal Chem. 2004 Aug 1;76(15):4537-42.