JTV-519 free base (Synonyms: K201 free base) |
Catalog No.GC36371 |
La base libre JTV-519 (base libre K201) est un bloqueur dépendant de Ca2 de l'ATPase stimulée par Ca2 du réticulum sarcoplasmique (SERCA) et un agoniste partiel des récepteurs de la ryanodine dans le muscle strié.
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Cas No.: 145903-06-6
Sample solution is provided at 25 µL, 10mM.
JTV-519 free base (K201 free base) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Cardioprotective agent[1].
[1]. Darcy YL, et al. K201 (JTV519) is a Ca2+-Dependent Blocker of SERCA and a Partial Agonist of Ryanodine Receptors in Striated Muscle. Mol Pharmacol. 2016 Aug;90(2):106-15.
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