Innate Immunity

PAR1 (1-6) is a hexapeptide that corresponds to amino acid residues 1-6 of the amino terminal tethered ligand sequence of mouse and rat proteinase-activated receptor 1 (PAR1), residues 42-47 of the full-length mouse sequence, and residues 46-51 of the full-length rat sequence.

7α-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7α-hydroxy cholesterol by GC- or LC-MS.

(-)-Epigallocatechin gallate-d3/d4 is intended for use as an internal standard for the quantification of (-)-epigallocatechin gallate by GC- or LC-MS.

LTB3 is the LTA hydrolase metabolite of LTA3 in the leukotriene biosynthetic pathway.

(±)18-HEPE is produced by non-enzymatic oxidation of EPA.

5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils by a specific dehydrogenase.

5-OxoETE is a polyunsaturated keto acid formed by the oxidation of 5-HETE in human neutrophils by a specific dehydrogenase.

Biosynthesis of 12(R)-HETE in invertebrates is via lipoxygenation of arachidonic acid.

15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway.

15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway.

(±)11(12)-EET est un inhibiteur de l'inflammasome NLRP3.

(±)9(10)-EpOME is the 9,10-cis epoxide of linoleic acid, generated by neutrophils during the oxidative burst.

Tiopronin is an antioxidant that has diverse biological activities.

C-178 is a covalent inhibitor of STING.

24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.

Kahweol is a natural diterpene that is isolated from coffee beans.

15-keto Prostaglandin E2 (15-keto PGE2) is a metabolite of PGE2 formed by 15-hydroxy PGDH.

Lipoxin A5 (LXA5) is produced by enzymatic transformation of EPA by leukocytes.

tetranor-Misoprostol is a metabolite of misoprostol.

La diméthoxycurcumine est un dérivé de la curcumine qui possède des activités anti-inflammatoires et antioxydantes.

L-erythro Sphingosine is a synthetic stereoisomer of sphingosine (d18:1).

(±)9(10)-DiHOME est le racémate de 9,10-DiHOME.

(±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME, a cytochrome P450-derived epoxide of linoleic acid also known as isoleukotoxin.

FTY720 is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs.