SLV 320 (Synonyms: SLV 320) |
| Catalog No.GC14290 |
Le SLV 320 (SLV 320) est un antagoniste des récepteurs A1 de l'adénosine puissant, sélectif et actif par voie orale, avec des valeurs Ki de 1 nM, 200 nM et 398 nM pour les récepteurs humains A1, A3 et A2A respectivement.
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Cas No.: 251945-92-3
Sample solution is provided at 25 µL, 10mM.
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Derenofylline (SLV 320) is a potent, selective and orally active adenosine A1 receptor antagonist, with Ki values of 1 nM, 200 nM and 398 nM for human A1, A3 and A2A receptors respectively. Derenofylline suppresses cardiac fibrosis and attenuates albuminuria without affecting blood pressure in rats[1].
References:
[1]. Kalk P, et al. The adenosine A1 receptor antagonist SLV320 reduces myocardial fibrosis in rats with 5/6 nephrectomy without affecting blood pressure. Br J Pharmacol. 2007 Aug;151(7):1025-32.
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