G1

Thiamine antagonist and inhibitor of saccharomyces cerevisiae transketolase. RaÏs et al. indicated that oxythiamine inhibits the growth of Ehrlich's tumor cells.

A naturally occurring prostaglandin with antiviral/antitumor activity

4-Hydroxyretinoic acid (4-HRA) is a naturally occurring, primary metabolite derived from all-trans retinoic acid (ATRA) via cytochrome P450 enzyme metabolism.

Fascaplysin (chloride) is an antimicrobial and cytotoxic red pigment, that can come from the marine sponge (Fascaplysin (chloride)opsis sp.

D-Cyclins regulate the cell cycle by acting in a complex with cyclin dependent kinases (CDKs) to promote phosphorylation of the retinoblastoma protein and initiate cellular progression from the G1 to the S phase.

Bostrycin is an anthraquinone originally isolated from B.

Zymostenol is a late-stage precursor in the biosynthesis of cholesterol.

D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase (Ki = 2-13 μM; IC50 = 1-5 μM).

2-deoxy-Artemisinin is an inactive metabolite of the antimalarial agent artemisinin.

C2 L-erythro Ceramide is a bioactive sphingolipid and a cell-permeable analog of naturally occurring ceramides.

C2 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.

Dihydroartemisinic acid is a biosynthetic precursor to the antimalarial agent artemisinin and an intermediate in the synthesis of artemisinin from artemisinic acid .

CAY10503 is a proapoptotic, antiproliferative compound that is able to arrest cell cycle progression in the G0-G1 phase.

6α-hydroxy Paclitaxel is a primary metabolite of the anticancer compound paclitaxel, produced by the action of the cytochrome P450 isoform CYP2C8.

CDK/CRK inhibitor is an inhibitor of cyclin-dependent kinases (CDK) and CDK-related kinases (CRK) with IC50 values ranging from 9-839 nM in vitro.

Chromomycin A2 is an aureolic acid that has been found in several marine actinomycetes and has antibacterial and anticancer activities.

CPTH6 is a thiazole derivative that inhibits the lysine acetyltransferase activity of Gcn5 and pCAF but not p300 or CBP.

Post-translational protein prenylation is a 3-step process that occurs at the C-terminus of a number of proteins involved in cell growth control and oncogenesis.

Didymin is a flavonoid that has been found in citrus fruits with diverse biological activities.

Kazusamycin B is a bacterial metabolite originally isolated from Streptomyces.

Methylcarbamyl PAF C-8 is the C-8 analog of Methylcarbamyl PAF C-16.

NVP-BEZ235 is a potent dual inhibitor of phosphatidylinositol 3-kinase (PI3K) and mTOR that is well tolerated, displays disease stasis when administered orally, and enhances the efficacy of other anticancer agents when used in in vivo combination studies.

Protein tyrosine phosphatases (PTPs) remove phosphate from tyrosine residues of cellular proteins.

A withanolide with anti-inflammatory and anticancer activities