Gastric Disease

Stachyose is an oligosaccharide and prebiotic.

Virstatin is an inhibitor of the ToxT transcriptional regulator of V.

BAR501 impurity is an impurity found in the preparation of BAR501 that acts as an agonist of the G protein-coupled bile acid-activated receptor (GP-BAR1).

R-(-)-α-Methylhistamine (hydrochloride) is a potent, selective and brain-penetrant agonist of H3 histamine receptor, with a Kd of 50.3 nM.

8-Nitroguanine is a nitrative guanine derivative formed by oxidative damage to the guanine base in DNA by reactive nitrogen species (RNS) during inflammation and in vitro by reaction of DNA with peroxynitrite and other RNS reagents.

BC-1215 is an inhibitor of F-box protein 3 (FBXO3; IC50 = 0.9 μg/mL for Il-1β release).

13,14-dihydro-15-keto Prostaglandin E1 (PGE1) is a metabolite of PGE1 with much reduced biological activity.

Nigakinone is one of the most abundant alkaloids responsible for the major pharmacological activities of Kumu.

Tetrahydrocoptisine ((RS)-Stylopine) (Tetrahydrocoptisine) is an alkaloid compound originally isolated from Corydalis tubers that exhibits anti-inflammatory and anti-parasitic activities.

all-trans Retinoic acid-d5 is intended for use as an internal standard for the quantification of all-trans retinoic acid by GC- or LC-MS.

(-)-Epigallocatechin gallate-d3/d4 is intended for use as an internal standard for the quantification of (-)-epigallocatechin gallate by GC- or LC-MS.

N-acetyl-5-Aminosalicylic acid is a metabolite of the anti-inflammatory agent 5-aminosalicylic acid and its prodrug form, sulfasalazine.

Tiopronin is an antioxidant that has diverse biological activities.

tetranor-Misoprostol is a metabolite of misoprostol.

The lipid messenger ceramide is converted to glucosylceramide by glucosylceramide synthase (GCS).

Hecogenin is a natural steroid sapogenin with diverse biological activities that was originally isolated from A.

Adrenocorticotropic hormone (ACTH) (1-10) is an N-terminal peptide fragment of ACTH, a peptide hormone produced by the anterior pituitary gland that is involved in the biological stress response.

Caerulein is an oligopeptide originally isolated from skin extracts of H.

Cholesterol β-D-glucoside is a derivative of cholesterol that contains β-D-glucose.

Desacetyl bisacodyl (DAB) is an active metabolite of two stimulant laxatives, bisacodyl and sodium picosulfate.

ONO-AE3-208 is an antagonist of the EP4 receptor (Ki = 1.3 nM) that less potently affects EP3, FP, and TP receptors (Kis = 30, 790, and 2,400 nM, respectively) and is without effect on other prostanoid receptors.

Pantoprazole sulfone is a metabolite of the gastric H+/K+ ATPase pump inhibitor pantoprazole.

Taurocholic Acid (sodium salt) is a major bile acid in the form of conjugation with taurine and has significant biological activity.