(Z)-2-decenoic acid |
| Catalog No.GC35008 |
A natural fatty acid which disperses biofilms
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 15790-91-7
Sample solution is provided at 25 µL, 10mM.
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(Z)-2-decenoic acid(cis-2-Decenoic acid) is an unsaturated short chain fatty acid that is secreted by P. aeruginosa and induces a dispersion response in biofilms formed by gram-negative and gram-positive bacteria, as well as by the yeast C. albicans.
[1]. Davies DG,Marques CN (2009) A fatty acid messenger is responsible for inducing dispersion in microbial biofilms. Journal of bacteriology 191, 1393-403 [2]. Gu W, Silverman RB.Synthesis of (S)-2-Boc-Amino-8-(R)-(tert-butyldimethylsilanyloxy) decanoic acid, a Precursor to the Unusual Amino Acid Residue of the Anticancer Agent Microsporin B.Tetrahedron Lett. 2011 Oct 19;52(42):5438-5440. [3]. Petelska AD, Figaszewski ZA.Interfacial tension of the lipid membrane formed from phosphatidylcholine-decanoic acid and phosphatidylcholine-decylamine systems.J Membr Biol. 2011 May;241(2):103-8. [4]. Kumar A, Singh S, Jain S, Kumar P.Synthesis, antimicrobial evaluation, QSAR and in Silico ADMET studies of decanoic acid derivatives.Acta Pol Pharm. 2011 Mar-Apr;68(2):191-204. [5]. Naumowicz M, Petelska AD, Figaszewski ZA.Impedance analysis of complex formation equilibria in phosphatidylcholine bilayers containing decanoic acid or decylamine.Cell Biochem Biophys. 2011 Sep;61(1):145-55.
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