7-Epi 10-desacetyl paclitaxel (Synonyms: 10-Deacetyl-7-epitaxol, 10-Deacetyl-7-epi-paclitaxel, 10-Deacetyl-7-epipaclitaxel, 10-Desacetyl-7-epi-taxol, 10-Desacetyl-7-epipaclitaxel, 7-epi-10-deacetyl Paclitaxel, Ormosin VI) |
| Catalog No.GC35187 |
A taxane diterpenoid with α-glucosidase inhibitory and anticancer activities
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 78454-17-8
Sample solution is provided at 25 µL, 10mM.
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7-Epi 10-desacetyl paclitaxel (7-epi-10-deacetyltaxol), a taxol derivative, exhibits cytotoxicity against HeLa cells with an IC50 of 85 μM[1][2].
[1]. Fungal 7-epi-10-deacetyltaxol produced by an endophytic Pestalotiopsis microspora induces apoptosis in human hepatocellular carcinoma cell line (HepG2). [2]. Dang PH, et al.α-Glucosidase Inhibitory and Cytotoxic Taxane Diterpenoids from the Stem Bark of Taxus wallichiana. J Nat Prod. 2017 Apr 28;80(4):1087-1095.
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