GLPBio

7-Epi 10-desacetyl paclitaxel

Catalog No.: GC35187Purity:>99.00%Synonyms: 10-Deacetyl-7-epitaxol, 10-Deacetyl-7-epi-paclitaxel, 10-Deacetyl-7-epipaclitaxel, 10-Desacetyl-7-epi-taxol, 10-Desacetyl-7-epipaclitaxel, 7-epi-10-deacetyl Paclitaxel, Ormosin VI
COASDSData Sheet
A taxane diterpenoid with α-glucosidase inhibitory and anticancer activities

Products are for research use only. Not for human use. We do not sell to patients.

7-Epi 10-desacetyl paclitaxel
Cas No.: 78454-17-8
5mgIn Stock
$239.00
1
10mgIn Stock
$308.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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    Nature
    641, 529–536 (2025)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    35, 97–116 (2025)
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    31, 1291–1307 (2021)

Description

7-Epi 10-desacetyl paclitaxel (7-epi-10-deacetyltaxol), a taxol derivative, exhibits cytotoxicity against HeLa cells with an IC50 of 85 μM[1][2].

[1]. Fungal 7-epi-10-deacetyltaxol produced by an endophytic Pestalotiopsis microspora induces apoptosis in human hepatocellular carcinoma cell line (HepG2). [2]. Dang PH, et al.α-Glucosidase Inhibitory and Cytotoxic Taxane Diterpenoids from the Stem Bark of Taxus wallichiana. J Nat Prod. 2017 Apr 28;80(4):1087-1095.

Product Documents

Purity:>99.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
78454-17-8
Synonyms
10-Deacetyl-7-epitaxol, 10-Deacetyl-7-epi-paclitaxel, 10-Deacetyl-7-epipaclitaxel, 10-Desacetyl-7-epi-taxol, 10-Desacetyl-7-epipaclitaxel, 7-epi-10-deacetyl Paclitaxel, Ormosin VI
SMILES
O=C(N[C@@H](C1=CC=CC=C1)[C@@H](O)C(O[C@H]2C[C@@](O)([C@@H](OC(C3=CC=CC=C3)=O)[C@@]4([H])[C@@]5(C)[C@H](O)C[C@]6([H])[C@@]4(OC(C)=O)CO6)C(C)(C)C([C@@H](O)C5=O)=C2C)=O)C7=CC=CC=C7
Molecular Formula
C45H49NO13
Molecular Weight
811.87
Solubility
Soluble in DMSO
Storage
4°C, protect from light
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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