GLPBio

9-Dihydro-13-acetylbaccatin III

Catalog No.: GC35206Purity:>99.00%Synonyms: 9-Dihydro-13-acetylbaccatin III
9-Dihydro-13-acetylbaccatin III (9-DHAB III) is an intermediate for taxol analog preparations.

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9-Dihydro-13-acetylbaccatin III
Cas No.: 142203-65-4
10mM (in 1mL DMSO)In Stock
$58.00
1
5mgIn Stock
$42.00
1
10mgIn Stock
$65.00
1
25mgIn Stock
$133.00
1
50mgIn Stock
$214.00
1
100mgIn Stock
$348.00
1

Citations

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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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Description

9-Dihydro-13-acetylbaccatin III (9-DHAB III) is an intermediate for taxol analog preparations. IC50 value:Target: There are a series of closely related natural organic compounds isolated from the Pacific yew tree (Taxus brevifolia) and related species. Taxols have exhibit antitumor agents. 9-Dihydro-13-acetylbaccatin III is an antineoplastic agent and an anti-cancer intermediate.

[1]. Li S, Zhang P, Zhang M, Fu C, Yu L. Functional analysis of a WRKY transcription factor involved in transcriptional activation of the DBAT gene in Taxus chinensis. Plant Biol (Stuttg). 2013 Jan;15(1):19-26. [2]. Naill MC, Kolewe ME, Roberts SC. Paclitaxel uptake and transport in Taxus cell suspension cultures. Biochem Eng J. 2012 Apr 15;63:50-56. [3]. Qayum M, Nisar M, Shah MR, et al. Analgesic and antiinflammatory activities of taxoids from Taxus wallichiana Zucc. Phytother Res. 2012 Apr;26(4):552-6. [4]. Kevin Walker and Rodney Croteau. Taxol biosynthesis: Molecular cloning of a benzoyl- CoA:taxane 2α-O-benzoyltransferase cDNA from Taxus and functional expression in Escherichia coli. PNAS, 2000 , 97(25):13591-13596.

Product Documents

Purity:>99.00%Appearance:A solid

Chemical Properties

CAS No.
142203-65-4
Synonyms
9-Dihydro-13-acetylbaccatin III
SMILES
O[C@@H](C1)[C@]2(C)[C@]([C@@]3(OC(C)=O)[C@]1([H])OC3)([H])[C@H](OC(C4=CC=CC=C4)=O)[C@]5(O)C[C@H](OC(C)=O)C(C)=C(C(C)5C)[C@@H](OC(C)=O)[C@@H]2O
Molecular Formula
C33H42O12
Molecular Weight
630.68
Solubility
DMF: 10mg/mL,DMF:PBS (pH 7.2) (1:4): 0.2mg/mL,DMSO: 5mg/mL
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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