GLPBio

DIPQUO

Catalog No.: GC35868Purity:>98.00%
COASDSData Sheet
DIPQUO is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells.

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DIPQUO
Cas No.: 1269365-82-3
10mM (in 1mL DMSO)In Stock
$346.00
1
5mgIn Stock
$315.00
1
10mgIn Stock
$522.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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Description

DIPQUO is an activator of the bone marker alkaline phosphatase (ALP), with an EC50 of 6.27 μM in C2C12 cells. DIPQUO promotes mouse and human osteoblast differentiation via activation of p38 MAPK-β[1]. EC50: 6.27 μM (ALP, C2C12 cells)[1]

[1]. Cook B, et al. Discovery of a Small Molecule Promoting Mouse and Human Osteoblast Differentiation via Activation of p38 MAPK-β. Cell Chem Biol. 2019 Mar 29.

Product Documents

Purity:>98.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
1269365-82-3
SMILES
CC1=CC(C)=C(NC(C(C2=C(C3=CC=CC=C3)N=CN2)=C4)=O)C4=C1
Molecular Formula
C20H17N3O
Molecular Weight
315.37
Solubility
DMSO : 5 mg/mL (15.85 mM; ultrasonic and warming and heat to 60°C)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

Reviews

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