GLPBio

Fulvestrant R enantiomer

Catalog No.: GC36088Purity:>98%
COASDSData Sheet
Fulvestrant R enantiomer (ICI 182780 R enantiomer) is the R enantiomer of Fulvestrant. Fulvestrant is a potent estrogen receptor antagonist with an IC50 of 9.4 nM.

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Fulvestrant R enantiomer
Cas No.: 1807900-80-6
5mgIn Stock
$788.00
1
10mgIn Stock
$1,391.00
1
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Citations

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    641, 529–536 (2025)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    31, 1291–1307 (2021)

Description

Fulvestrant R enantiomer is the R enantiomer of Fulvestrant. Fulvestrant is a selective estrogen receptor (ER) antagonist which can be used to treat breast cancer.

[1]. Caprioglio D, et al. An alternative synthesis of the breast cancer drug fulvestrant (Faslodex•): catalyst control over C-C bond formation. Chem Commun (Camb). 2015 Oct 14;51(80):14866-8. [2]. Osborne CK, et al. Fulvestrant: an oestrogen receptor antagonist with a novel mechanism of action. Br J Cancer. 2004 Mar;90 Suppl 1:S2-6.

Chemical Properties

CAS No.
1807900-80-6
SMILES
C[C@@]12[C@@H](O)CC[C@@]1([H])[C@]3([H])[C@H](CCCCCCCCC[S@](CCCC(F)(F)C(F)(F)F)=O)CC4=C(C=CC(O)=C4)[C@@]3([H])CC2
Molecular Formula
C32H47F5O3S
Molecular Weight
606.77
Solubility
Soluble in DMSO
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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