GLPBio

Glabrene

Catalog No.: GC36144Purity:>98%
COASDSData Sheet
Glabrene, an isoflavene derived from licorice root, shows estrogen-like activity.

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Glabrene
Cas No.: 60008-03-9
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Citations

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    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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Description

Glabrene, an isoflavene derived from licorice root, shows estrogen-like activity. Glabrene is a tyrosinase inhibitor with an IC50 of 3.5 μM[1][2]. IC50: 3.5 μM (Tyrosinase)[2]

[1]. Somjen D, et al. Estrogenic activity of glabridin and glabrene from licorice roots on human osteoblasts and prepubertal rat skeletal tissues. J Steroid Biochem Mol Biol. 2004 Aug;91(4-5):241-6. [2]. Nerya O, et al. Glabrene and isoliquiritigenin as tyrosinase inhibitors from licorice roots. J Agric Food Chem. 2003 Feb 26;51(5):1201-7

Chemical Properties

CAS No.
60008-03-9
SMILES
OC1=C2C=CC(C)(C)OC2=C(C3=CC4=CC=C(O)C=C4OC3)C=C1
Molecular Formula
C20H18O4
Molecular Weight
322.35
Solubility
Soluble in DMSO
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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